Regarding minerals, selenium is crucial for the proper conversion of the less active thyroid hormone, thyroxine (T4), into the metabolically active triiodothyronine (T3). Without selenium, the metabolically inactive reverse T3 (rT3) is created instead, putting our bodies in a metabolically disadvantageous state. Zinc, iodine, manganese, and copper are also necessary for the proper production of thyroid hormones, while zinc is also particularly important for increasing the sensitivity of thyroid receptors. All of these minerals are found in highly bioavailable forms, fully chelated with glycine for optimal stability and absorption.
With regard to vitamins, vitamin A is an interesting nutrient that appears to work synergistically with iodine to regulate thyroid health, while directly improving thyroid hormone transport and receptors on target tissues. In animals, vitamin A deficiency leads to reduced thyroid hormone synthesis and thyroid enlargement due to decreased iodine uptake. In children with even mild vitamin A deficiency, elevated TSH and less active T4 hormone have been observed. Interestingly, in iodide-deficient children, vitamin A supplementation led not only to improved iodide efficacy, but also to reduced TSH and a lower risk of hypothyroidism. Vitamin B12 is another important vitamin in some patients with thyroid problems, typically deficient in up to 55% of patients with autoimmune thyroid disease, possibly due to low stomach acid, malabsorption, or even autoimmune gastritis. Finally, we have plant extracts such as Bacopa monnieri and KSM-66® Withania somnifera that may have a positive impact on the progression of thyroid dysfunction. Bacopa is traditionally known for its ability to improve cognition and other areas of neurological function, but animal studies have suggested that it can significantly increase T4 concentrations. Additionally, bacopa has been shown to lower cortisol levels. Poor cognition and unbalanced cortisol levels are associated with thyroid dysfunction. Withania somnifera from KSM-66® is also better known for its adaptogenic properties and its ability to improve performance during times of stress. However, ashwagandha is a unique adaptogenic herb in that it has a specific affinity for supporting thyroid function, with various studies showing increased thyroid hormone secretion and increased TSH and T4 concentrations.
Collectively, all of these ingredients in Thyroid Matrix BA support thyroid health and thyroid hormones on multiple levels, allowing for a comprehensive and effective approach to a low-functioning thyroid. Thyroid Matrix BA with Bacopa can be considered a more robust formula compared to Thyroid Matrix, as it contains the addition of vitamins A, B12, Bacopa monnieri, and a higher dosage of Withania somnifera with a higher percentage of withanolide standardization (5% and 1.5%, respectively).
Adults: Take 1 capsule 3 times daily with food or as directed by a healthcare professional. Take a few hours before or after taking other medications or natural health products. Be sure to drink plenty of fluids before, during, and after exercise.
Ingredient (per capsule):L-Tyrosine 250mgKSM-66® Ashwagandha extract (root, Withania somnifera), 12:1, 5.0% withanolides, DHE 2400mg 200mgBacopa extract (higher plant, Bacopa monnieri) 50% bacosides 100mgZinc (TRAACS™ zinc bis-glycinate chelate) 5mgCopper (TRAACS™ copper bis-glycinate chelate) 666.66mcgVitamin A (all-trans retinyl palmitate) 503.66mcg / RAE (1666.66IU)Manganese (TRAACS™ manganese bis-glycinate chelate) 500mcgVitamin B12 (methylcobalamin) 333.33mcgIodine (Laminaria digitata/Ascophyllum nodosum) 133.33mcg Selenium (Albion™ selenium glycinate complex) 66.66mcg Nonmedicinal ingredients: Vegetable-grade magnesium stearate, microcrystalline cellulose, maltodextrin, citric acid, fumed silica, ascorbyl palmitate, vitamin E, glycine, sucrose, modified starch, brown rice flour. Capsule: hypromellose.