R-alpha-lipoic acid may have greater bioavailability than the synthetic mixture.
In vivo studies have shown that combinations of CLA and R-alpha-lipoic acid act synergistically to prevent mitochondrial degradation.
Standardized Ginkgo biloba extract promotes cognitive functioning, neuropsychiatric symptoms, and functional abilities in people with vascular dementia and Alzheimer's dementia.
Resveratrol, a potent antioxidant found in Japanese knotweed, improves muscle mitochondrial respiration in obese individuals, as well as several cardiometabolic risk factors.
Clinical trials indicate that administration of grape seed proanthocyanidins stimulates mitochondrial function in the skeletal muscle of obese Zucker rats and improves cognitive function in older adults. Suitable for vegetarians/vegans Oxidative damage to mitochondria is a major factor in cellular aging and neurological decline. While lifestyle interventions, such as calorie restriction, help improve mitochondrial function in young, non-obese adults, certain supplements such as L-carnitine also offer therapeutic benefits. The salt of L-carnitine, called acetyl-L-carnitine (ALC), is the preferred form in cases of disease and aging because it is better absorbed and easily crosses the blood-brain barrier. CLA has been shown not only to improve mood, but also to play an important role in aging disorders, including fatigue, hypertension, insulin resistance, diabetic neuropathy, and dementia.
Mito AMP also contains Ginkgo biloba extract, resveratrol, R-alpha-lipoic acid, and grape seed proanthocyanidins, all of which modulate mitochondrial function, improve cognitive function, and/or reduce inflammation associated with cognitive decline. Pyrroloquinoline quinone (PQQ) plays a key role in mitochondrial biogenesis through cellular signaling (PGC-1 alpha). Clinical trials have shown improved cerebral blood flow and brain function, improved memory when combined with CoQ10, as well as increased vigor and significant reductions in symptoms of fatigue, tension, low mood, and confusion.
Adults: 1 capsule 3 times daily with food or as directed by a healthcare practitioner. Consult a healthcare practitioner for use beyond 4 weeks.
Medicinal Ingredients: Acetylcarnitine (N-acetyl-L-carnitine hydrochloride) 300 mg Ginkgo Biloba Extract (Ginkgo biloba) (leaf) (24% Flavone Glycosides, 6% Terpene Lactones) 80 mg Japanese Knotweed Extract (Polygonum cuspidatum) (root) (20% Trans-Resveratrol) 66.67 mg Coenzyme Q10 (microorganism) 60 mg R-Alpha-Lipoic Acid 50 mg Grape Seed Extract (Vitis vinifera) (seed) (80% Oligomeric Proanthocyanidins) 30 mg BioPQQ® (pyrroloquinoline quinone disodium salt) 3.33 mg Nonmedicinal Ingredients: Vegetable capsule (carbohydrate gum [cellulose], purified water), silica, Vegetable-grade magnesium stearate (lubricant), microcrystalline cellulose.
