Phytoestrogenic herbs such as Angelica sinensis, Actaea racemosa, and Trifolium pretense have demonstrated various reductions in hot flashes and menopausal symptoms, in part due to their ability to bind weakly to estrogen receptors. Actea racemosa also has phytoestrogenic activity but may act more centrally on the brain and positively affect serotonin, dopamine, or opioids. While there is mixed research on the effectiveness of phytoestrogenic herbs in treating hot flashes, positive trials tend to favor extracts with standardized active ingredients or higher potency. Other herbs may be beneficial in relieving menopausal symptoms due to mechanisms external to estrogen. For example, Vitex agnus-castus, commonly known as chasteberry, acts more as a progestin herb, while Diascorea villosa is a well-known antispasmodic herb. Hypericum perforatum is best known for its ability to regulate mood and improve symptoms of depression, but it has also been shown to reduce the severity of hot flashes in postmenopausal women.
Fem-Matrix from Cyto-Matrix combines a blend of these research-driven herbs to reduce perimenopausal and menopausal symptoms, including hot flashes. Each herb is in a highly extracted form and standardized to active ingredients to ensure potency and effectiveness. Fem-Matrix also includes the bioflavonoids quercetin and hesperidin to improve blood vessel integrity and reduce hot flashes.
Adults: Take 2 capsules twice daily before meals or as directed by a healthcare professional.
Ingredients (per capsule): Dong quai extract (Angelica sinensis) 5:1, 1% ligustilides 60 mg Black cohosh extract (root and rhizome, Actaea racemosa) 3:1, 2.5% triterpene glycosides 50 mg Hesperidin 125 mg Quercetin 125 mg Chasteberry extract (fruit, Vitex agnus-castus) 10:1 50 mg Wild yam extract (root, Dioscorea villosa) 10:1 50 mg St. John's wort extract (higher plant, Hypericum perforatum) 4:1, 0.3% hypericin 30 mg Red clover extract (flower, Trifolium pratense) 10:1 20 mg Non-medicinal ingredients: Vegetable grade magnesium stearate, Microcrystalline cellulose, maltodextrin, silicon dioxide. Capsule: hypromellose.