- Methylcobalamin is the active form of vitamin B12 for maximum benefit.
- Higher bioavailability than the most common form, cyanocobalamin, which does not convert to sufficient methylcobalamin to correct some forms of anemia, neurological defects, and aging1.
- Reduces homocysteine levels for protective effects on the cardiovascular system
- Sublingual tablets provide rapid action directly into the bloodstream.
Description
Vitamin B12 is the cofactor of enzymatic reactions with various physiological functions. It is necessary for the conversion of methylmalonyl CoA to succinyl CoA, as well as the conversion of homocysteine to methionine by methionine synthase, which is then converted to S-adenosylmethionine. B12 deficiency leads to deficiencies in these two pathways, disrupting neurological function, including poor formation of myelin sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.
Methylcobalamin, the major circulating form of B12 and the one that is transported to peripheral tissues, has been shown to reduce not only homocysteine, but also inflammatory factors and carotid artery plaque volume in patients with suffered a stroke, as well as pain and neuropathy in diabetics. Due to its relationship with myelin production and neurological function, high dose B12 has been used in various neurodegenerative diseases, including Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.
Some people, especially those with malabsorption or low dietary intake, are at greater risk of B12 deficiency. People with poor B12 absorption rely on passive absorption, which is typically 1% of the amount ingested. Therefore, high doses may be necessary for people with higher B12 needs, such as the elderly and those with neurodegenerative disorders.
Dosage
Adults: 1 tablet per day or as recommended by a healthcare professional. Dissolve under the tongue. Consult a health care practitioner for use beyond 4 months.
Nutritional information
Medicinal ingredients: Vitamin B12 (Methylcobalamin) 5000 mcg
Nonmedicinal ingredients: Lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, vegetable grade magnesium stearate (lubricant).
[/TABS]Adultes : 1 comprimé par jour ou selon les recommandations d'un professionnel de la santé. Dissoudre sous la langue. Consulter un praticien de soins de santé pour une utilisation au-delà de 4 mois.
Ingrédients médicinaux : Vitamine B12 (Méthylcobalamine) 5000 mcg Ingrédients non médicinaux : Lactose monohydraté, cellulose microcristalline, croscarmellose sodique, stéarate de magnésium de qualité végétale (lubrifiant).
