B12 Folate

Activated Vitamin B12 and Folic Acid B12 Folate is a combination of two water-soluble B vitamins, folate and vitamin B12. Folate and vitamin B12 have an interconnected function. They are essential for nutrient metabolism and are both required by the enzyme that produces methionine. They are also essential for maintaining red blood cell homeostasis, as they contribute to red blood cell formation. At the molecular level, folate's main function is to donate methyl groups in key biochemical reactions. Adequate folate status is particularly important for proper neural and cellular development of the fetal central nervous system. Folate promotes healthy cellular differentiation during brain and spinal cord formation, helping to reduce the risk of neural tube defects when taken daily before becoming pregnant and during early pregnancy. Folate is provided in this formula as Metafolin®, the universally metabolized form of folate. Metafolin® is chemically identical to the active metabolite of folic acid, 5-methyltetrahydrofolate (L-5-MTHF). L-5-MTHF is the primary natural form of folic acid found in foods. Because it bypasses several steps of enzyme activation, it is directly usable by the body and provides all the benefits of folic acid, regardless of functional or genetic variations. The vitamin B12 in this formula is provided as methylcobalamin, the most bioavailable form of this vitamin.