Berberis Formula

Combination of berberine extracts from natural plant sources Traditionally used in Herbal Medicine as a bitter to aid digestion and relieve digestive disorders such as dyspepsia and as a mild laxative Includes goldenseal root extract, barberry root and stem extract, barberry root bark, and Oregon grape root extract Berberis Formula is a blend of barberry, goldenseal, and Oregon grape extracts, traditionally used in Herbal Medicine to maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine. Recent research has shown that berberine prevents bacteria from adhering to the gastric mucosa. Berberine also controls ion and water transport in intestinal epithelial cells. It helps maintain the balance between electrolytes and water, resulting in an antidiarrheal effect. Berberine can increase the expression of Na+, H+ exchanger, and aquaporin, which improves sodium and water absorption, respectively. Berberine also promotes the formation of a proper intestinal epithelial nexus and decreases the permeability of these cells to promote proper gastrointestinal barrier function. During stages of low contractility, berberine stimulates the jejunum by activating muscarinic receptors, resulting in increased intestinal motility and a mild laxative effect.