Offers a comprehensive range of protective compounds from cruciferous vegetables, including I3C, DIM, and sulforaphane.
Provides a unique blend of botanicals that enhance estrogen metabolism, shunting away carcinogenic metabolites.
Promotes the detoxification of a variety of environmental toxins as well as naturally produced hormones by enhancing phase 1 and phase 2 liver enzymes.
Contains botanicals with potent anti-inflammatory activity.
Suitable for vegetarians/vegans
EstroVantage EM provides a comprehensive formula of plant-derived compounds that enhance the metabolism of estrogens and their metabolites. Cruciferous vegetables contain a variety of glucosinolates, which some studies have linked to a reduced incidence of cancer when consumed in higher amounts, most likely by causing a shift in metabolism toward less carcinogenic estrogen metabolites. EstroVantage EM contains indole-3-carbinol (I3C) and its metabolite 3,3'-diindolylmethane (DIM), as well as sulforaphane from broccoli powder, all of which have been linked to lower rates of neoplastic changes and a more favorable estrogen profile. Not only do these glucosinolates improve estrogen metabolism, but they also reduce inflammation by targeting key signaling molecules, such as Nrf2 and NF-κB.
EstroVantage EM also contains other potent plant compounds that reduce inflammation and block cancer-causing pathways. Silymarin, a milk thistle extract, downregulates gene products involved in tumor cell proliferation, as well as invasion, angiogenesis, and metastasis. This unique combination contains green tea polyphenols, lycopene (tomato extract), turmeric and rosemary extracts, and calcium D-glucarate, which have been shown to favorably alter estrogen metabolism and reduce carcinogenic risk. Most recently, a randomized, double-blind, placebo-controlled crossover study demonstrated that taking this formula resulted in significantly higher urinary levels of the protective estrogen metabolite 2-OHE1 and lower levels of the more dangerous estrogen metabolite 16α-OHE1 in premenopausal women.
Adults: 3 capsules once daily with food or as directed by a healthcare practitioner. Consult a healthcare practitioner for use beyond 12 weeks.
Medicinal Ingredients: Calcium D-Glucarate (calcium salt of d-glucaric acid) 75 mg Indole-3-Carbinol (3-Hydroxymethylindole) 75 mg Green Tea Extract (Camellia sinensis) (leaf) (80% catechins, 45% EGCG*, <1% caffeine) 50 mg Tomato Extract (Lycopersicon esculentum) (fruit) (5% Lycopene) 50 mg Broccoli Powder (Brassica oleracea var. italica) (aerial) (0.36% Sulforaphane) 27.5 mg DIM (3,3'-Diindolylmethane) 25 mg Turmeric Extract (Curcuma longa) (rhizome) (95% Curcuminoids) 25 mg Milk Thistle Extract (Silybum marianum) (seed) (50-60% silymarin) 25 mgRosemary Extract 6:1 (Rosmarinus officinalis) (leaf) 12.5 mg
Nonmedicinal ingredients: Vegetable capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable-grade magnesium stearate (lubricant), silica.
