{"title":"Bioclinic Naturals","description":"","products":[{"product_id":"emiq-activated-quercetin","title":"EMIQ Activated Quercetin","description":"Most absorbable form of quercetin\nOffers 40 times greater absorption than regular quercetin\nProvides 167 mg of enzymatically modified isoquercitrin (EMIQ), providing 50 mg of quercetin, plus 50 mg of vitamin C per capsule\nProvides anti-inflammatory, antioxidant, anti-allergy, and cardiovascular benefits\nSuitable for vegetarians and vegans\n\nQuercetin, a dietary flavonol known to be one of the most potent plant-derived antioxidants, has multiple biological actions, with preclinical studies showing anti-inflammatory, antithrombotic, and vasodilatory benefits. The limiting factor in the clinical efficacy of quercetin appears to be its low bioavailability. Enzymatically modified isoquercitrin (EMIQ) is a mixture of quercetin monoglucoside and its alpha-oligoglucosides that has been shown to have significantly higher bioavailability than other available forms. In animals, EMIQ has been shown to produce a 40-fold increase in Cmax (peak plasma concentration) and an 18-fold increase in area under the curve compared to quercetin. In humans, EMIQ supplementation increased plasma concentrations to a significantly greater extent than other forms, including the aglycone and isoquercitrin (Q3G) forms. Randomized, placebo-controlled trials have shown EMIQ to have clinical benefits not seen with less absorbable forms. In a recent crossover trial in volunteers at risk for cardiovascular disease (i.e., those with elevated blood pressure, lipids, glucose, or waist circumference), EMIQ improved endothelial function (as measured by flow-mediated vasodilation), a key risk factor for hypertension, atherosclerosis, and cardiovascular disease. American football players taking whey protein supplements experienced greater increases in lower limb muscle mass and antioxidant protection when they consumed 42 mg of EMIQ per day compared to whey alone. Two trials found that EMIQ reduced medication use and ocular symptoms of hay fever due to Japanese cedar pollinosis.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43117089128619,"sku":"emiq-activated-quercetin-bioclinic-naturals-60c","price":27.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/EMIQ-activated-quercetin-Assured-naturals-60c.png?v=1749234772"},{"product_id":"glutathione-lipomicel","title":"Glutathione LipoMicel","description":"Provides the reduced form of glutathione, GSH.\nGlutathione is the primary cellular antioxidant, protecting against many types of cellular damage.\nLipoMicel® technology creates a liquid micellar matrix that disperses glutathione into tiny microdroplets, resulting in a highly stable delivery system for higher absorption than standard forms.\nClinically effective dose, 300 mg per capsule.\n\n\u003cspan style=\"font-size: 0.875rem;\"\u003eGlutathione is the most abundant intracellular antioxidant, not only providing protection against reactive oxygen and nitrogen species, but also playing a major role in multiple functions that maintain cellular homeostasis. Present in every cell, glutathione plays a role in immune function, gene expression, mitochondrial integrity, regulation of DNA and protein synthesis, and detoxification of endogenous and environmental toxins.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eWhile most intracellular glutathione is in a reduced state (GSH) with approximately 1% in the oxidized form (GSSG), this proportion can decrease in response to a variety of cellular stressors, including heavy metals, high glucose concentrations, poor diet, heat shock, reactive oxygen and nitrogen species, cigarette smoke, and other toxins, including persistent organic pollutants. Indeed, it is declining GSH levels that have been linked to many chronic and age-related diseases, as well as the aging process itself. .\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eGlutathione supplementation has been clearly shown to increase GSH levels at multiple sites in human clinical trials, including plasma, red blood cells, and lymphocytes. Additionally, improved delivery forms such as liposomal glutathione and polymeric micelles (liquid micelle matrix) improve bioavailability, confer resistance to intestinal degradation, and may also improve intracellular glutathione delivery, bypassing potential enzymatic bottlenecks.\u003c\/span\u003e\u003cbr\u003e\n","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43117149487275,"sku":"glutathione-lipomicel-bioclinic-naturals-60gel","price":42.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/Glutathione-lipomicel-bioclinic-naturals-60gel.png?v=1749234772"},{"product_id":"nac-500mg","title":"NAC 500mg","description":"Supports the synthesis of glutathione, a key cellular antioxidant and conjugator of many environmental toxins.\nImproves endothelial function and supports nitric oxide synthesis. 500 mg of NAC per capsule allows for easy and therapeutic dosage levels.\nStable and well-absorbed form of the readily oxidizable amino acid L-cysteine.\n\nN-acetyl-L-cysteine ​​(NAC) is known for its various physiological and therapeutic benefits, largely attributed to its antioxidant, anti-inflammatory, and mucolytic effects. It is well known to increase glutathione, a key intracellular antioxidant, by providing a stable form of L-cysteine, the rate-limiting factor in glutathione synthesis. The number of conditions with impaired glutathione homeostasis continues to grow, including not only cardiovascular, neurodegenerative, pulmonary, and age-related diseases, but there is also increasing clinical recognition of metabolic disturbances related to exposure to environmental toxins, such as diabetes and persistent organic pollutants. By restoring glutathione levels, NAC is also well established as the most effective treatment for acetaminophen toxicity.\u003cbr\u003e\u003cbr\u003eAdditionally, NAC's ability to cleave disulfide bonds gives it efficacy as a mucolytic agent, with clinical benefit for people with COPD and pulmonary fibrosis. Disulfide bond breaking may also be the same mechanism by which it lowers homocysteine ​​and improves endothelial function in coronary artery disease. NAC has immunomodulatory and anti-inflammatory effects, improving flu symptoms and SLE activity. By modulating glutamatergic and neurotropic pathways, NAC has also been shown to be beneficial for schizophrenia, bipolar disorder, and autism.","brand":"Bioclinic Naturals","offers":[{"title":"90 capsules","offer_id":43117169639595,"sku":"NAC-bioclinic-naturals-90c","price":19.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/NAC-bioclinic-naturals.jpg?v=1749234771"},{"product_id":"nac-ala","title":"NAC \u0026 ALA","description":"\n\nProvides clinically relevant doses of N-acetyl-L-cysteine ​​(NAC) and alpha-lipoic acid (ALA)\n\nNAC and ALA have direct antioxidant action and enhance the synthesis and regeneration of glutathione, the key cellular antioxidant.\n\nSupports mitochondrial function and the upregulation of phase II antioxidant enzymes\n\nTargets central mediators of inflammation\n\nImproves endothelial function and supports nitric oxide synthesis\n\nReduces damage associated with hyperglycemia\n\nSuitable for vegetarians\n\nNAC and ALA are highly complementary nutrients, essential for cellular function and mitigating damage associated with hyperglycemia. NAC stimulates the synthesis of glutathione, which is often depleted in cardiovascular disease and conditions of metabolic and oxidative stress. NAC also has direct antioxidant activity, restores intracellular thiol pools, and has an anti-inflammatory effect, mediated by inhibition of nuclear factor kappa B (NF-kB). Glutathione is required for the detoxification of many persistent organic pollutants, compounds known to impair mitochondrial function, adipose tissue metabolism, and pancreatic islet cell function. In addition to glutathione support, NAC enhances antioxidant protection through multiple pathways, including upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activation and phosphoinositide 3-kinase\/protein kinase B (PI3K\/AKT), suggesting significant potential for mitigating oxidative stress pathology. Clinical trials have shown that NAC restores intraplatelet glutathione levels in certain populations—a marker of atherothrombotic risk—reduces homocysteine, and improves endothelial function in coronary artery disease (at doses of 600 to 1,800 mg\/day).\u003cbr\u003e\u003cbr\u003eALA, in turn, recycles antioxidant nutrients such as vitamin C and glutathione, and is a cofactor for several mitochondrial enzymes as well as glutathione reductase. It supports glycemic control and insulin sensitivity in individuals with inadequate glycemic control, endothelial function in individuals with impaired glucose tolerance, and weight control in obese subjects. It has a well-recognized benefit in mitigating neuronal oxidative damage resulting from hyperglycemia. Clinical trial data have shown improvement in several markers of oxidative stress and vascular inflammation in various populations. Its antioxidant and neuroprotective effects may also provide protection against neurodegeneration and a range of oxidant-related diseases.","brand":"Bioclinic Naturals","offers":[{"title":"90 capsules","offer_id":43117263749291,"sku":"nac-ala-bioclinic-naturals-90c","price":34.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/NAC-ALA-Bioclinic-naturals-90c.png?v=1749234770"},{"product_id":"coq10-200-mg","title":"CoQ10 200 mg","description":"Improves many health conditions, including cardiovascular disease, cellular breakdown, and oxidative stress.\nFree from contamination by unwanted residues, including bacteria or yeast.\nContains natural rice bran oil and natural vitamin E to ensure a stabilized and highly absorbable form of CoQ10.\n\nThe majority of CoQ10's clinical uses are based on its role as an antioxidant and its role in mitochondrial bioenergetics. It is a coenzyme for many reactions involved in cellular respiration and is necessary for the efficient formation of adenosine triphosphate (ATP), the cellular currency that fuels most enzymatic reactions. As an antioxidant, CoQ10 is the only endogenously synthesized fat-soluble antioxidant. It inhibits the peroxidation of cell membrane lipids and circulating lipoproteins. CoQ10 supports cardiac tissue by improving endothelial function and exerting a direct anti-atherogenic effect, resulting in lower blood pressure and improved ventricular contractility.\nIn clinical trials, CoQ10 has been shown to be beneficial for a wide range of cardiovascular conditions, including congestive heart failure, hypertension, and the prevention of myocardial infarction. It has also been shown to be beneficial for several neurological conditions, including Huntington's disease, migraine, and Parkinson's disease. Oral CoQ10 has also shown positive results in patients with periodontal disease, gingivitis, male infertility, and statin-induced myopathy.","brand":"Bioclinic Naturals","offers":[{"title":"30 Capsules","offer_id":43152802676907,"sku":"80028367-30g","price":21.99,"currency_code":"CAD","in_stock":true},{"title":"60 Capsules","offer_id":43152802709675,"sku":"80028367-60g","price":37.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/pmldw9qpxzd8gmgn2yuw.jpg?v=1749234703"},{"product_id":"coq10-400-mg","title":"CoQ10 400 mg","description":"Identical to the form produced by the human body for high bioavailability\nImproves many health conditions, including cardiovascular disease, cellular breakdown, and oxidative stress.\nThe higher 400 mg dosage reduces the need to take multiple pills throughout the day and aligns with evolving research.\nFree from contamination by unwanted residues or microorganisms, including bacteria or yeast\nIn a base of natural rice bran oil and vitamin E to ensure a stabilized and highly absorbable form of CoQ10.\n\nThe majority of CoQ10's clinical uses are based on its role as an antioxidant and its role in mitochondrial bioenergetics. It is a coenzyme for many reactions involved in cellular respiration and is necessary for the efficient formation of adenosine triphosphate (ATP), the cellular currency that fuels most enzymatic reactions. It inhibits the peroxidation of cell membrane lipids as well as circulating lipoproteins.3,4 CoQ10 supports cardiac tissue by improving endothelial function and having a direct anti-atherogenic effect, which results in lower blood pressure and improved ventricular contractility.\u003cbr\u003e\u003cbr\u003eHigh doses of CoQ10, up to 2400 mg per day, have been used primarily for neurodegenerative diseases such as Parkinson's disease and Huntington's disease, although high doses have also been used in patients with severe cardiovascular disease or advanced breast cancer. Clinical trials have shown benefits for a wide range of cardiovascular conditions, including congestive heart failure, hypertension, and prevention of myocardial infarction. It has also shown clinical benefits for a number of other conditions, including migraine, periodontal disease, gingivitis, male infertility, and statin-induced myopathy.","brand":"Bioclinic Naturals","offers":[{"title":"30 Capsules","offer_id":43152802775211,"sku":"80028342","price":37.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/zc8tjegdkrial34bjabv.jpg?v=1749234702"},{"product_id":"optimega-3-r-epa-400-mg-dha-200-mg","title":"OptiMega-3® EPA 400 mg · DHA 200 mg","description":"Optimal 2:1 ratio of EPA to DHA in a highly bioavailable softgel.\n\nPharmaceutical-grade omega-3 fish oil blend, verified by the USP for quality and consistency.\n\nFree of lipid peroxides and environmental pollutants, including heavy metals, pesticides, dioxins, PCBs, and other harmful compounds.\n\nHarvested using sustainable fishing practices.\n\nSourced from wild-caught anchovies, sardines, and\/or mackerel, one of nature's best sources of EPA and DHA.\n\nThe omega-3 fatty acids in fish oil improve several cardiovascular risk factors, including decreasing atherosclerotic burden, lowering triglyceride levels and blood pressure, and improving platelet and vascular function. Not only do these fatty acids modulate risk factors, but controlled clinical trials have shown them to be effective in preventing cardiovascular and coronary events, particularly in high-risk individuals.\u003cbr\u003e\u003cbr\u003eEPA and DHA also support cognitive function through multiple mechanisms, as they are essential for neuronal membranes, lower levels of which have been shown to be not only a marker of neurological disease but also a risk factor for cognitive impairment. EPA and DHA are essential for resolving inflammatory processes, providing substrates for the anti-inflammatory prostaglandins, resolvins, and protectins.\nBenefits have also been demonstrated for improving overall health, including a wide variety of cardiovascular, inflammatory, and autoimmune conditions, ranging from cardiac arrhythmias, eczema, and inflammatory bowel disease, to pregnancy and lactation support, rheumatoid arthritis, and neurodegenerative diseases. Meta-analyses of randomized trials found that supplementation improved lipids and HbA1c and reduced proteinuria in diabetics, and improved insulin sensitivity in people with at least one symptom of a metabolic disorder.","brand":"Bioclinic Naturals","offers":[{"title":"180 Capsules","offer_id":43152802807979,"sku":"80012786","price":42.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/t6crpcgvnfaziokiwyxa.jpg?v=1749234702"},{"product_id":"optimega-3-r-with-vitamin-d3","title":"OptiMega-3® with Vitamin D3","description":"Convenient once-daily dosing in a highly bioavailable softgel\u003cbr\u003e\n\nPharmaceutical-grade omega-3 blend, verified by the USP for quality and consistency.\u003cbr\u003e\n\nOptimal 2:1 ratio of EPA to DHA for convenient once-daily dosing.\u003cbr\u003e\n\nFree of lipid peroxides and environmental pollutants, including heavy metals, pesticides, dioxins, PCBs, and other harmful compounds.\nSourced from wild-caught anchovies, sardines, and\/or mackerel, among the best natural sources of EPA and DHA.\u003cbr\u003e\n\nHarvested using sustainable fishing practices.\n\nVitamin D and the omega-3 fatty acids in fish oil are among the most powerful nutrients for improving overall health, and they are also among the most commonly deficient. EPA and DHA improve several cardiovascular risk factors, including decreasing atherosclerotic burden, lowering triglyceride levels and blood pressure, and improving platelet and vascular function. Not only do these fatty acids modulate risk factors, but controlled clinical trials have shown them to be effective in preventing cardiovascular and coronary events, particularly in high-risk individuals. EPA and DHA also support cognitive function through multiple mechanisms, as they are essential for neuronal membranes, with lower levels proving not only a marker of neurological disease but also a risk factor for cognitive impairment. EPA and DHA are essential for resolving inflammatory processes, providing substrates for the anti-inflammatory prostaglandins, resolvins, and protectins. Vitamin D modifies cardiovascular risk and reduces the risk of autoimmune diseases and osteoporotic fractures. It has also been shown to have anti-inflammatory effects, with supplementation being particularly important for those showing signs of inflammation. Inadequate intake of vitamin D and EPA\/DHA has been implicated in brain dysfunction, including impaired serotonin activation, cognitive decline, ADHD, and mood disorders. EPA and DHA combined with vitamin D have synergistic beneficial effects on improving overall well-being.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152802840747,"sku":"80066571","price":39.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/an3obcqcgymoxiyzi8gw.jpg?v=1749234701"},{"product_id":"optimega-3-r-with-vitamin-d3-lemon-meringue-flavour","title":"OptiMega-3® with Vitamin D3 · lemon meringue flavor","description":"\nOptimal 2:1 ratio of EPA to DHA for convenient once-daily dosing.\n\nClinical strength of 1500 mg of EPA and 750 mg of DHA in triglyceride form, and 1000 IU of vitamin D3 per teaspoon.\n\nPharmaceutical-grade omega-3 blend, verified for quality and consistency by the USP.\n\nFree of lipid peroxides and environmental pollutants, including heavy metals, pesticides, dioxins, PCBs, and other harmful compounds.\n\nSourced from wild-caught anchovies, sardines, and\/or mackerel, among nature's best sources of EPA and DHA.\n\nHarvested using sustainable fishing practices.\n\nLemon flavor.\n\n\u003cspan style=\"font-size: 0.875rem;\"\u003eVitamin D and omega-3 fatty acids in fish oil are among the most powerful nutrients for improving overall health, but also among those most commonly deficient. EPA and DHA improve several cardiovascular risk factors, including decreasing atherosclerotic burden, reducing triglyceride levels and blood pressure, and improving platelet and vascular function. Not only do these fatty acids modulate risk factors, but controlled clinical trials have shown them to be effective in preventing cardiovascular and coronary events, particularly in high-risk individuals.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eEPA and DHA also support cognitive function through multiple mechanisms, as they are essential for neuronal membranes, with lower levels being not only a marker of neurological disease but also a risk factor for cognitive impairment. EPA and DHA are essential for resolving inflammatory processes, providing substrates for anti-inflammatory prostaglandins, resolvins, and protectins. Vitamin D modifies cardiovascular risk and reduces the risk of autoimmune diseases and osteoporotic fractures. It has also been shown to have anti-inflammatory effects, with supplementation being particularly important for individuals showing signs of inflammation. Inadequate intake of vitamin D and EPA\/DHA has been implicated in brain dysfunction, including impaired serotonin activation, cognitive decline, ADHD, and mood disorders. EPA and DHA, combined with vitamin D, have synergistic benefits for improving overall well-being.","brand":"Bioclinic Naturals","offers":[{"title":"200ml","offer_id":43152802873515,"sku":"80073481","price":39.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/mdv9hmpoxyjbpmcmmq2g.jpg?v=1749234700"},{"product_id":"optimega-3-r-q10","title":"OptiMega-3® Q10","description":"\nOptimal 2:1 EPA\/DHA ratio in a highly bioavailable softgel\u003cbr data-mce-fragment=\"1\"\u003e\n\nProvides 600 mg of EPA, 300 mg of DHA, and 100 mg of CoQ10 per softgel\u003cbr data-mce-fragment=\"1\"\u003e\n\nPharmaceutical-grade omega-3 blend, verified by the USP for quality and consistency\u003cbr data-mce-fragment=\"1\"\u003e\n\nFree of lipid peroxides and environmental pollutants, including heavy metals, pesticides, dioxins, PCBs, and other harmful compounds.\u003cbr data-mce-fragment=\"1\"\u003e\n\nSourced from wild-caught anchovies, sardines, and\/or mackerel, among nature's best sources of EPA and DHA.\u003cbr data-mce-fragment=\"1\"\u003e\n\nHarvested using sustainable fishing practices\n\nThis Highly potent combination of CoQ10 and omega-3 fatty acids EPA\/DHA provides cardiovascular and cognitive benefits through multiple distinct and overlapping pathways. CoQ10 and EPA\/DHA have been shown to improve endothelial function, particularly in populations at risk for atherosclerosis (high BMI, metabolic syndrome, smoking, hyperlipidemia), with clinically significant hypotensive and anti-atherogenic effects.\u003cbr\u003e\u003cbr\u003eCoQ10 plays a critical role in oxidative phosphorylation and mitochondrial bioenergetics, which are essential for neuronal health and the prevention of mitochondrial dysfunction that underlies many chronic diseases, including neurodegenerative diseases. In addition, recent data highlight an emerging role for CoQ10 in reducing inflammation and insulin resistance, which are important contributors to impaired cognitive function. A meta-analysis of randomized trials showed that CoQ10 and EPA\/DHA supplementation reduced key biomarkers of inflammation, including C-reactive protein, TNF-alpha, and IL-6. Serum CoQ10 levels have also been associated with neurological outcomes after ischemic stroke, as well as the risk of debilitating dementia. OptiMega-3 Q10 also provides high doses of pharmaceutical-grade EPA\/DHA, which has been shown to reduce numerous cardiovascular risk factors and improve vascular function, with controlled clinical trials demonstrating a reduction in the rate of cardiovascular and coronary events, particularly in high-risk individuals. Omega-3 fatty acids have been linked to a reduction in myocardial infarction and stroke, with supplementation mitigating adverse left ventricular changes, myocardial fibrosis, and systemic inflammation after myocardial infarction. EPA\/DHA supports cognitive function through multiple mechanisms, as both are essential for neuronal membranes, with lower levels being not only a marker of neurological disease but also a risk factor for cognitive impairment.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803037355,"sku":"80029633","price":37.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/zedlpgzcz7zpfj8lzuvg.jpg?v=1749234700"},{"product_id":"ubiquinol-coq10-100-mg","title":"Ubiquinol CoQ10 100 mg","description":"Cardiovascular Support\nOffers a highly absorbable and bioavailable form of CoQ10 (ubiquinol)\nIncreases plasma CoQ10 levels significantly higher per mg than ubiquinone\nProvides higher peak plasma CoQ10 levels, with 100 mg per softgel reflecting clinical trial dosing\nKaneka Q+ brand ubiquinol is naturally produced by yeast fermentation and is free from synthetically processed CoQ10 impurities.\nAn organic flaxseed oil base improves solubility and provides ALA-rich omega-3 fatty acids\nNon-Genetically Modified Organisms (GMOs), allergen-free, and Kosher certified\n\nCoQ10 is commonly referred to as ubiquinone because it is ubiquitous throughout the body and present in nearly every cell. The active form of the molecule, ubiquinol, is a fat-soluble antioxidant that protects fats such as those that make up cell and mitochondrial membranes, as well as HDL and LDL cholesterol. However, CoQ10's most important role is in cellular respiration, the process of generating the energy (ATP) that all cells need for optimal health. Because its role in energy production is so critical, it is especially important in cells with high energy needs, such as the heart. This helps explain why CoQ10 has been shown to be so beneficial for conditions affecting the cardiovascular system, such as high blood pressure, cardiomyopathy, protection during heart surgery, and protection against statins used to treat high cholesterol. Low CoQ10 levels have also been reported for many other conditions, with clinical trials supporting the use of CoQ10 for migraines, male infertility, Alzheimer's disease (prevention) and Parkinson's disease (prevention and treatment), and macular degeneration. Moderate doses, ranging from 300 to 600 mg per day, have been used for statin-related myopathy, female infertility (decreased ovarian reserve), and multiple sclerosis.\u003cbr\u003e\u003cbr\u003eKaneka Q+ Ubiquinol provides the form of CoQ10 found in 95% of human tissues. Higher levels of ubiquinol compared to ubiquinone are indicative of greater cellular protection.14 Kaneka Q+ Ubiquinol has also been shown to be more soluble than ubiquinone, more effectively increasing blood levels of this nutrient so essential for energy production. The organic flaxseed oil base improves the solubility of ubiquinol and provides heart-healthy omega-3 fatty acids. Flaxseed oil is particularly rich in alpha-linolenic acid, an anti-inflammatory oil associated with improved cardiovascular health.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803070123,"sku":"ubiquinol-100mg-bioclinic-naturals-60c","price":44.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/cogk7uuqg2mvahgprnqn.jpg?v=1749234699"},{"product_id":"ubiquinol-coq10-200-mg","title":"Ubiquinol CoQ10 200 mg","description":"Cardiovascular Support\nOffers a highly absorbable and bioavailable form of CoQ10 (ubiquinol)\nIncreases plasma CoQ10 levels significantly more per mg than ubiquinone\nProvides higher peak plasma CoQ10 levels, with 200 mg per softgel reflecting clinical trial dosing.\nKaneka Q+ brand ubiquinol is naturally produced by yeast fermentation and is free from synthetically processed CoQ10 impurities.\nAn organic flaxseed oil base improves solubility and provides ALA-rich omega-3 fatty acids.\nNon-Genetically Modified Organisms (GMOs), allergen-free, and Kosher certified.\n\nCoQ10 is commonly referred to as ubiquinone because it is ubiquitous throughout the body and present in nearly every cell. The active form of the molecule, ubiquinol, is a fat-soluble antioxidant that protects fats such as those that make up cell and mitochondrial membranes, as well as HDL and LDL cholesterol. However, CoQ10's most important role is in cellular respiration, the process of generating the energy (ATP) that all cells need for optimal health. Because its role in energy production is so critical, it is especially important in cells with high energy needs, such as the heart. This helps explain why CoQ10 has been shown to be so beneficial for conditions affecting the cardiovascular system, such as high blood pressure, cardiomyopathy, protection during heart surgery, and protection against statins used to treat high cholesterol. Low CoQ10 levels have also been reported for many other conditions, with clinical trials supporting the use of CoQ10 for migraines, male infertility, Alzheimer's disease (prevention) and Parkinson's disease (prevention and treatment), and macular degeneration. Moderate doses, ranging from 300 to 600 mg per day, have been used for statin-related myopathy, female infertility (decreased ovarian reserve), and multiple sclerosis.\u003cbr\u003e\u003cbr\u003eKaneka Q+ Ubiquinol provides the form of CoQ10 found in 95% of human tissues. Higher levels of ubiquinol compared to ubiquinone are indicative of greater cellular protection.14 Kaneka Q+ Ubiquinol has also been shown to be more soluble than ubiquinone, more effectively increasing blood levels of this nutrient so essential for energy production. The organic flaxseed oil base improves the solubility of ubiquinol and provides heart-healthy omega-3 fatty acids. Flaxseed oil is particularly rich in alpha-linolenic acid, an anti-inflammatory oil associated with improved cardiovascular health.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803135659,"sku":"ubiquinol-200mg-bioclinic-naturals-60c","price":88.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/bx0qzk8sufdnttwa4hs6.jpg?v=1749234698"},{"product_id":"bioclear","title":"BioClear™","description":"Promotes toxin elimination and enhances glutathione synthesis with NAC, green tea extract, taurine, and glutathione, essential for the elimination of many endogenous and exogenous toxins.\nIncludes nutrients that improve metabolic function and support glucose regulation, including chromium picolinate and magnesium citrate.\nProvides a broad base of bioavailable nutrients, including folate 5-MTHF, riboflavin 5-phosphate, and methylcobalamin, as well as the citrate\/picolinate forms of most minerals.\nIn a low-allergen organic pea and rice protein base, providing over 8g of each protein per serving.\n\nBioClear supports detoxification pathways by providing key nutrients from a wide range of bioavailable vitamins and minerals. This formula uses forms of each nutrient designed to both bypass metabolic bottlenecks and for optimal absorption, including riboflavin 5-phosphate, the 5-MTHF form of folate, mixed tocopherols, and the citrate or picolinate forms of most minerals. BioClear's low-allergen organic pea and rice proteins not only complement an elimination diet, being soy- and dairy-free, but pea protein in particular provides a complete protein at least as effective as whey for muscle building.\u003cbr\u003e\u003cbr\u003eClinical nutrients such as N-acetyl-cysteine ​​(NAC), glutathione, taurine, and green tea extract support the detoxification of endogenous and exogenous toxins. NAC has been shown to directly increase cellular glutathione levels, limiting toxicity and improving the elimination of numerous toxins, including mercury, lead, cadmium, and a variety of persistent organic pollutants. Taurine provides antioxidant support, increases mitochondrial protein synthesis, and has been shown to improve cardiac and endothelial function.","brand":"Bioclinic Naturals","offers":[{"title":"1 kg","offer_id":43152803168427,"sku":"80073269","price":66.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/ht6ogfhxhautykheksoz.jpg?v=1749234698"},{"product_id":"biolivx","title":"BioLivX™","description":"A specific blend of nutrients and traditional herbs designed to promote liver tissue health.\nContains sodium glucuronate, a key nutritional substance used by the liver to bind toxins.\nIntense liver support.\nPromotes healthy detoxification of liver toxins and excess hormones.\nAntioxidant protection neutralizes free radical damage.\nReduces oxidative stress and its effects on the body.\nSuitable for vegetarians\/vegans.\n\nBioLivX contains a variety of nutrients and herbs proven to protect and improve liver function and support detoxification pathways. Sodium glucuronate supports the Phase II detoxification pathway by providing the precursor to glucuronidation. The conjugation of glucuronic acid with a wide variety of functional groups, including hydroxyls, phenols, and carboxyls, occurs in the liver and intestine.\u003cbr\u003e\u003cbr\u003eLicorice has been shown to have hepatoprotective effects, including protection against toxins such as carbon tetrachloride, as well as against the excess free fatty acids that accompany non-alcoholic fatty liver disease. Alpha-lipoic acid is a water- and fat-soluble antioxidant involved in hepatoprotection and the prevention of cellular damage. It has the ability to alter the redox status of cells and interact with thiols, thereby increasing the glutathione content of the liver.\u003cbr\u003e\u003cbr\u003eSilybin is the most active flavonolignan isomer of silymarin. It acts through several pathways, including antioxidant, antilipid peroxidant, antifibrotic, anti-inflammatory, and liver regenerative mechanisms. It also improves glucuronidation and protects against glutathione depletion. Schizandra, curcumin, and Panax ginseng are also hepatoprotective, supporting detoxification pathways and improving liver function.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152803463339,"sku":"80049992","price":35.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/jhbzq8xknefgibbdjcsg.jpg?v=1749234697"},{"product_id":"activated-charcoal-250mg","title":"Activated Charcoal Capsules","description":"Provides activated charcoal at a dose associated with the relief of symptoms of excess gas, including bloating, pressure, pain, and a feeling of choking.\nActivated charcoal binds to a variety of intestinal toxins and other compounds, preventing their safe absorption.\nThe softgel form is easy to swallow.\nContains no artificial colors, preservatives, sweeteners, or GMOs.\n\nActivated charcoal has been used for over 100 years, primarily for its ability to bind and remove toxins and other compounds, including gas, from the body. Activating the charcoal creates a highly developed porous structure with a high surface area containing carbon groups, such as carbonyl and hydroxyl groups. These groups bind to a variety of toxins in the gastrointestinal (GI) tract within minutes of contact, minimizing their systemic absorption. Activated charcoal binds to toxins without being absorbed and passes through the gastrointestinal tract unchanged, without altering the microbiome.\u003cbr\u003e\u003cbr\u003eSeveral clinical trials also indicate that activated charcoal can reduce intestinal gas by directly absorbing gas or gas-producing substrates. In a double-blind clinical trial using lactulose as a substrate, activated charcoal reduced both exhaled hydrogen levels and abdominal bloating and cramping attributed to excess gas. It has been shown to be effective in reducing the amount of gas present when administered before an abdominal ultrasound without side effects, thereby improving the visualization that intestinal gas can obscure.\u003cbr\u003e\n","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152803496107,"sku":"2537680","price":27.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/dwv3mhs8tuwgdwcnu2uq.jpg?v=1749234696"},{"product_id":"betaine-hci-with-100-mg-fenugreek","title":"Betaine HCI with 100 mg Fenugreek","description":"Naturally sourced from beetroot\n500 mg of betaine HCl per capsule allows for flexible dose titration\nSuitable for vegetarians and vegans\n\nBetaine hydrochloride increases hydrochloric acid (HCl) in the stomach to improve digestion, while fenugreek helps soothe and protect the stomach lining. Low stomach acidity is more common with age and can be associated with several health problems. The combination of betaine HCl and fenugreek may help stimulate digestion and soothe the digestive tract.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eHCl aids in protein digestion by activating pepsinogen to pepsin, helping to inactivate orally ingested pathogens, preventing bacterial or fungal overgrowth in the small intestine, encouraging the flow of bile and pancreatic enzymes, and facilitating the absorption of several nutrients, including vitamin B12, ascorbic acid, calcium, iron, and magnesium. However, maldigestion can occur in the absence of adequate HCl, leading to bloating, belching, indigestion, diarrhea, or constipation. Numerous studies have shown that acid secretion declines with age, and impaired HCl production and secretion are associated with a variety of clinical conditions. Although the underlying etiological factors leading to impaired or absent HCl secretion are not well understood, long-term supplementation is generally safe and may be effective in certain patient populations and clinical conditions. Combining betaine hydrochloride with fenugreek further supports digestive function and health, as fenugreek seeds are an excellent source of mucilage, which may help relieve gastrointestinal inflammation by coating the stomach and intestinal walls.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803528875,"sku":"80053147","price":12.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/mgooounbor26rrvpvd7v.jpg?v=1749234695"},{"product_id":"childrens-multi-probiotic","title":"Children's Multi Probiotic","description":"Contains a probiotic blend of seven Lactobacillus and Bifidobacterium species, which are associated with a healthy gut microbiome during childhood.\n\nProvides a guaranteed minimum of 3 billion active cells per serving.\nThe powder is easy to dose and mix with other foods\/beverages.\nNo added flavors, colors, or sugars; gluten-free.\n\nChildren's Multi-Probiotic provides a clinical dose of seven Lactobacillus and Bifidobacterium probiotic species associated with healthy gastrointestinal function and the natural microbiome established during childhood. A healthy microbiota has been linked to a wide range of beneficial functions, including modulation of the immune system, improved response to vaccination, improved health of the cells lining the gastrointestinal tract and gastrointestinal barrier, and resistance to pathogenic bacterial species. Many of the beneficial effects of a healthy microbiota have been attributed to its metabolites, such as short-chain fatty acids (SCFAs) and bile acids, which have both local and systemic effects.\n\u003cbr\u003eThe species contained in Children's Multi-Probiotic have been shown to have several specific benefits. For example, Bifidobacterium longum subspecies infantis has been described as a \"champion of infant gut colonization,\" linked to reduced inflammation and a better response to vaccines. A meta-analysis suggests that Lactobacillus fermentum may be the most effective species for reducing the severity of atopic dermatitis in children. Similarly, several Lactobacillus and Bifidobacterium species, particularly L. casei, reduce the risk of developing C. difficile-associated diarrhea after antibiotic use. Several large meta-analyses have also found a significant reduction in respiratory tract infections in children supplemented with probiotics.","brand":"Bioclinic Naturals","offers":[{"title":"60g","offer_id":43152803659947,"sku":"80033530","price":31.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/zoq3mls1kvg2llwebkpx.jpg?v=1749234694"},{"product_id":"dgl-400-mg","title":"DGL · 400 mg","description":"Provides DGL in chewable tablets, the form associated with the greatest clinical efficacy, as it allows licorice to be released in the stomach and dispersed\/absorbed through the gastric mucosa.\nProvides 400 mg of DGL per tablet, the clinically effective dose.\nDeglycyrrhizination prevents adverse effects associated with licorice consumption.\nPleasant-tasting tablets for improved compliance.\nSuitable for vegetarians\/vegans.\n\nDeglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers. Licorice contains numerous triterpenoids and hundreds of flavonoids that have been shown to inhibit several inflammatory enzymes, including cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). These enzymes decrease the production of several potent inflammatory compounds, including IL-6, prostaglandin E2, thromboxane B2, and leukotriene B4. Importantly, this inhibition is not primarily due to glycyrrhizic acid, the licorice component that was eliminated in DGL and is associated with mineralocorticoid excess and hypertension. Licorice contains numerous active compounds with anti-inflammatory, antimicrobial, and anti-allergic actions, including glabridin and at least seven licochalcones. These compounds have been shown to prevent lipopolysaccharide (LPS)-induced production of inflammatory compounds, inhibit yeast and bacterial biofilm formation, and stimulate antioxidant enzymes.\nClinically, DGL has been shown to be comparable in efficacy to cimetidine for ulcer healing and prevention of recurrence. Furthermore, licorice extracts have been shown to inhibit the adhesion of H. pylori to the gastric mucosa, as well as the growth of antibiotic-resistant strains, suggesting multiple mechanisms of action for its anti-ulcer effect. The use of chewable tablets appears necessary for the efficacy of DGL, as they allow distribution and absorption through the gastric mucosa.","brand":"Bioclinic Naturals","offers":[{"title":"180 Chewable Tablets","offer_id":43152803725483,"sku":"80037407","price":24.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/ssp4ojnhgxkkippwlwu7.jpg?v=1749234693"},{"product_id":"digest-progd-hp","title":"Digest-ProGD HP","description":"Provides fungal and bacterial proteases to hydrolyze difficult-to-digest proline-containing peptides, such as gluten and casein.\nProvides broad-spectrum carbohydrate digestion with plant-derived papain, bromelain, and fungal digestive enzymes.\nThe high-potency formulation allows for easy dosing, with nearly 300 mg of enzyme blend in each vegetarian capsule.\nPerfectly suitable for vegetarians and vegans.\n\nDigest-ProGD HP is a high-potency, patented enzyme blend for complete carbohydrate digestion. It contains fungal proteases derived from Aspergillus oryzae, bacterial proteases from Bacillus subtilis, and comprehensive carbohydrate digestion support with papain, bromelain, and fungal digestive enzymes. Aspergillus oryzae extracts are rich in prolyl endopeptidases and dipeptidyl peptidase IV (DPP-IV)—a multifunctional serine protease that targets proline-containing peptides, such as those found in gliadin and casein, two proteins resistant to proteolysis.\nIndeed, the protease activity of Aspergillus oryzae targets the proline-rich 33-mer of gliadin, perhaps the most immunotoxic peptide derived from gliadin. The proline-rich antigenic and immunomodulatory proteins found in gluten are thought to trigger an inflammatory response in patients with celiac disease or gluten sensitivity, often due to accidental gluten exposure, even in individuals on a gluten-free diet. Aspergillus oryzae protease supplementation has also been associated with a bifidogenic effect in animals, suggesting a potential probiotic effect, as well as an increase in gut-protective amino acids.\u003cbr\u003e\u003cbr\u003eIn addition to fungal and bacterial proteases, Digest-ProGD HP provides alpha-amylase, cellulose, and hemicellulose for comprehensive carbohydrate digestion support.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803758251,"sku":"80072201","price":31.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/nma2kydqhd4a4wrvz6q1.jpg?v=1749234693"},{"product_id":"elementall-biological-diet-chocolate","title":"ElementAll Biological Diet","description":"Hypoallergenic formula, with 100% of the protein derived from free amino acids, particularly L-glutamine, an essential fuel for intestinal cells.\nContains easily assimilated and tolerated carbohydrates.\nAll nutrient needs are met, while requiring little or no digestive function to break down macronutrients.\nExcellent taste for improved compliance.\n\nElementAll Biological Diet is an elemental diet formula that provides complete, hypoallergenic, and easily digestible nutrition for individuals with digestive disorders. The therapeutic efficacy of elemental diets has been partly attributed to the elimination of all allergens (while providing nutrients requiring minimal digestion). This promotes healing of the gastrointestinal mucosa, normalization of intestinal permeability, and improvement of clinical symptoms in participants with Crohn's disease (as determined by the lactulose\/L-rhamnose permeability ratio). In people newly diagnosed with Crohn's disease, a complete elemental diet induces remission in over 80% of patients, while a \"semi-elemental diet\" significantly reduces relapse rates when followed longer-term.\nElemental diets target the gut microbiota as well as inflammation; in addition to suppressing levels of NF-κB (a critical regulator of inflammation), they significantly reduce the population of Bacteroides fragilis, a species linked to inflammatory bowel disease (IBD) and colorectal cancer. Among people with irritable bowel syndrome (IBS) and abnormal lactulose breath tests (indicating small intestinal bacterial overgrowth [SIBO]), 85% experienced normalization of breath values ​​and improvement in symptoms after following an elemental diet. Elemental diets have also resulted in similar improvement to corticosteroid therapy in people with rheumatoid arthritis, as well as immunopathological and clinical improvement in people with refractory celiac disease.\nThe ElementalAll Biological Diet provides all essential micro- and macronutrients optimized for easy absorption and is designed to be the sole source of nutrition for people with impaired digestive function.","brand":"Bioclinic Naturals","offers":[{"title":"Chocolate","offer_id":43152803823787,"sku":"elementall-biological-diet-bioclinic-naturals","price":119.99,"currency_code":"CAD","in_stock":true},{"title":"Vanilla \/ Coconut","offer_id":43918277247147,"sku":"elementall-biological-diet-bioclinic-naturals-vanille","price":119.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/jm94a95rc3qqcftq22un.jpg?v=1749234692"},{"product_id":"ib-care","title":"IB Care™","description":"Provides clinically effective amounts of peppermint, caraway, and oregano oils at proven dosages.\n\nPotent amounts of active ingredients: 50% menthol (peppermint), 60% phenol (oregano), and 50% carvone (caraway).\n\nEnteric coating enhances efficacy, providing an antispasmodic effect in the gastric and upper intestinal tissues.\n\nResearch confirms that peppermint oil is more effective and better tolerated when protected from stomach acid.\n\nEnteric coating also reduces side effects and the peppermint taste.\n\nIB Care contains enteric-coated peppermint, oregano, and caraway oils, which have been shown to have beneficial effects on various gastrointestinal disorders. Peppermint oil is known to influence gastric motility by accelerating early gastric emptying through its antispasmodic effect on the stomach. It also increases pyloric valve relaxation time, decreases lower esophageal sphincter resting pressure, and is beneficial when combined with caraway oil by producing smooth muscle relaxation in the stomach and duodenum. Oregano oil has demonstrated antimicrobial effects against H. pylori, the primary cause of peptic ulcer disease and dyspepsia, as well as other gastrointestinal pathogens.\nClinically, enterally coated preparations of these oils have demonstrated benefits in several clinical trials. A meta-analysis of twelve randomized trials involving a total of 835 patients with irritable bowel syndrome (IBS) compared the effects of peppermint oil with those of a placebo. Compared with the placebo group, patients taking peppermint oil experienced significant improvements in overall symptoms and abdominal pain. Controlled trials have shown improvements in dyspepsia and symptoms such as abdominal pain, heaviness, and pressure, regardless of H. pylori status, and even in patients with significant epigastric pain. Furthermore, enteric-coated peppermint oil has demonstrated clinical efficacy in several IBS trials, showing improvement in the majority of participants, both in children and adults.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803856555,"sku":"80052526","price":17.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/lcu0kbimktpszkhjh2ts.jpg?v=1749234691"},{"product_id":"probiotic-pro12-12-billion-active-cells","title":"Probiotic-Pro12 · 12 Billion","description":"A blend of multiple strains that approximates the normal composition of the intestinal flora and ensures balance throughout the intestinal tract.\nProvides 8 human-derived strains, 3 dairy-derived strains, and 1 plant-derived strain.\nEach strain has specific inhibitory functions against pathogenic and putrefactive microorganisms throughout the gastrointestinal tract.\nEach strain is resistant to gastric acidity and high bile concentrations.\nHigh potency with at least 12 billion CFU per capsule at the expiration date (guaranteed minimum of 18 billion active cells at the manufacturing date).\nContains the prebiotic FOS (fructooligosaccharides) inulin to promote probiotic growth.\u003cbr\u003e\u003cbr\u003e\n\nThe microbial ecosystem of the gastrointestinal (GI) tract has become a \"virtual organ system,\" whose importance in maintaining health and preventing disease is increasingly recognized. The GI microbiota plays a critical role in maintaining innate and cell-mediated immune system homeostasis and improves intestinal barrier function through several mechanisms, including toxin metabolism, tight junction protein phosphorylation, and inflammation reduction. Research has clearly demonstrated the importance of gut bacteria not only in maintaining optimal gastrointestinal health, but also in chronic and systemic diseases such as type 2 diabetes, obesity, and other inflammatory or autoimmune diseases.\u003cbr\u003e\u003cbr\u003eProbiotics have multifactorial benefits, modulating gut immune responses and intestinal barrier functions in a strain- and dose-dependent manner. Furthermore, probiotic blends appear to be more effective than individual strains, perhaps due to synergistic activity or because individuals respond differently to different strains.\u003cbr\u003e\u003cbr\u003eProbiotic-Pro12 contains 12 bacterial species, each chosen for its ability to withstand stomach acid and high bile concentrations, as well as for its clinically proven benefits through individual mechanisms of action. High-quality lactic acid bacteria require considerable care at all times, which is why more than 20 rigorous quality control measures are implemented to ensure strain consistency and product quality.\u003cbr\u003e\n","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803889323,"sku":"probiotic-pro12-bioclinic-naturals-60c","price":25.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/ly3hpdseaqcksljppkjo.jpg?v=1749234690"},{"product_id":"probiotic-pro-bb536-r-10-billion-active-cells","title":"Probiotic-Pro BB536® · 10 Billion Active Cells","description":"High Potency: 10 billion CFU (colony-forming units) of Bifidobacterium longum BB536 per capsule\nSuperior shelf stability compared to other Bifidobacterium species\u003cbr\u003eBB536 is one of the most studied species in the world.\nIts resistance to gastrointestinal acidity allows the formula to reach the large intestine.\nStable at room temperature; refrigeration is not necessary\nSuitable for vegetarians\/vegans\n\nProbiotic-Pro BB536 is a high-potency probiotic containing 10 billion CFU per capsule of the species Bifidobacterium longum BB536, one of the most studied in the world. This is a patented strain with a remarkably longer and more stable shelf life than other probiotic supplements, and a lower loss rate than other Bifidobacterium strains exposed to multiple different temperatures.\u003cbr\u003e\u003cbr\u003eIsolated from healthy human digestive tracts, Bifidobacterium has long been recognized as a beneficial genus, constituting over 90% of the total gastrointestinal bacteria in breastfed infants. It has been shown to have multiple immunomodulatory effects, such as increasing secretory IgA production and NK cell and neutrophil activity, as well as balancing Th1 and Th2 immune activity. It has also been shown to improve mucosal barrier function in the colon, in part by upregulating tight junction molecules. In clinical trials, BB536 supplementation has been shown to reduce allergy symptoms, decrease influenza infection, lower serum cholesterol levels, normalize bowel movements, reduce pathogenic bacterial populations, and promote normalization of gastrointestinal tissue.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803922091,"sku":"probiotic-pro-bb536-bioclinic-naturals-60c","price":35.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/viuav7r8sllyutswqicq.jpg?v=1749234690"},{"product_id":"ashwagandha-600-mg","title":"Ashwagandha 600 mg","description":"Provides 600 mg per softgel of proprietary, clinically studied organic Ashwagandha™ KSM-66 extract.\nIncludes dairy-free KSM-66 extract, made only from the plant's roots, with randomized clinical trials documenting its efficacy and safety for a range of conditions.\nExtracted using a proprietary water-based \"green chemistry\" process, without the use of alcohol or chemical solvents.\nStandardized to 5% withanolides, providing various physiological benefits.\nSuitable for vegetarians and vegans.\n\nAshwagandha (Withania somnifera) has long been used as a fundamental adaptogen in Ayurvedic medicine. It is credited with numerous benefits, including increased resistance to stress and anxiety, improved physical performance and immune function, as well as improved fertility, sleep, and neurological function. Its diverse phytochemistry includes withanolides, sitoindosides, phenolic compounds, and flavonoids, which help explain its diverse physiological actions, ranging from cardio- and neuroprotective to anti-inflammatory and anxiolytic effects.\nKSM-66 is a full-spectrum ashwagandha extract using only the roots of the plant, notable for the large number of randomized, controlled trials documenting its efficacy. Clinical trials have demonstrated significant improvements in symptoms and cortisol levels in participants suffering from chronic stress, as well as improved weight control and food cravings in this population. It has also been shown to improve overall well-being, sleep quality, and mental alertness in older adults, as well as memory and executive function in individuals with cognitive impairment. Clinical trials document increased cardiorespiratory endurance, as measured by VO2 max, in male and female athletes using KSM-66, as well as greater increases in muscle mass and strength when combined with resistance training. Additionally, KSM-66 extract has demonstrated benefits in improving sleep quality, enhancing sexual function in both men and women, restoring sperm activity in oligospermic men, and improving thyroid function in individuals with subclinical hypothyroidism.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152803954859,"sku":"80116512","price":30.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/pnmo6unqhpxiauuvblmg.jpg?v=1749234689"},{"product_id":"inspir-action","title":"Inspir-Action™","description":"Mucolytic, demulcent, and antitussive action for the relief of coughs, bronchitis, sinusitis, congestion, and other respiratory conditions.\n\nRespiratory formula containing a unique combination of herbs and nutrients designed to reduce symptoms and restore function.\n\nClinically relevant dosages of each active ingredient.\n\nNAC also increases levels of glutathione, a key antioxidant in lung tissue.\n\nInspir-Action® provides a powerful combination of nutrients and herbs to relieve symptoms and improve respiratory function. N-acetyl-L-cysteine ​​(NAC) is a well-known mucolytic with the ability to break disulfide bonds and has shown clinical benefits for people with COPD, bronchiectasis, and pulmonary fibrosis. NAC has also been shown to reduce symptoms of influenza-like infection, increase glutathione and sulfotransferase levels, inhibit activation of the NF-kB inflammatory pathway, and modulate immune function.\nProteolytic enzymes can reduce the viscosity of mucous secretions, and in a randomized trial, bromelain reduced symptoms of acute sinusitis in children more effectively than standard treatment. Marshmallow is widely used for coughs and soothing irritated mucous membranes, with mucilaginous and bioadhesive effects attributed to polysaccharides extracted from the root. English ivy extract increases bronchial beta-2-adrenergic activity, relaxing bronchial smooth muscles, and increasing surfactant factors. It has been shown to be an effective treatment for acute bronchitis and improves lung function in asthmatic children when used alongside standard drug therapy. Mullein, wild cherry, and black horehound extracts also have a long history of use for various respiratory tract conditions. These ingredients complement this formula with a unique combination of demulcent, emollient, expectorant, and cough suppressant properties to relieve symptoms.","brand":"Bioclinic Naturals","offers":[{"title":"60 Tablets","offer_id":43152804118699,"sku":"80040826","price":21.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/olta5zcum3lljttfxp8s.jpg?v=1749234688"},{"product_id":"immunealign","title":"ImmuneAlign™","description":"Provides a clinically proven dose of ECHINAMIDE®, a triple-standardized formulation of Echinacea purpurea for its active components (alkylamides, polysaccharides, and cichoric acid levels) using the whole herb (roots and flowers).\n\nECHINAMIDE is extracted from certified organic Echinacea grown in Canada, following GLP and GMP standards from seed to shelf.\n\nProprietary blend of ECHINAMIDE and potent antiviral herbal extracts of lomatium, astragalus, reishi mushroom, and licorice for a synergistic effect on immune function.\n\nEasy-to-swallow softgels\nThe tincture allows for easy dosing and is suitable for vegans\/vegetarians.\n\nThe antiviral formula offers a synergistic combination of five clinically validated herbal extracts, standardized to ensure optimal potency and efficacy. ECHINAMIDE is a well-established formulation of organically grown Echinacea purpurea, triple-standardized for key constituents (alkylamides, cichoric acid, and polysaccharides) that have been shown to enhance immune function and significantly reduce cold symptoms in randomized clinical trials. ECHINAMIDE stimulates the nonspecific immune system, increasing the total number of leukocytes, neutrophils, monocytes, and natural killer cells. Its alkylamides have anti-inflammatory and immunomodulatory effects, in part by binding to cannabinoid receptors on immune cells. Polysaccharides and polyphenols induce cell-mediated immunity and help stabilize secretory IgA levels. Although meta-analyses generally support the use of echinacea as an antiviral, standardization of its key components is essential to ensure clinical benefit. This powerful antiviral formula also contains extracts of lomatium and reishi mushroom, long-used antiviral herbs. Reishi contains triterpenoids that inhibit both viral entry and replication, and lomatium has in vitro inhibitory effects on rotavirus and blocks the production of CXCL10, a key signaling molecule for influenza and other viral infections. Extracts of echinacea, licorice, and astragalus have been shown to increase the production of CD25 and act synergistically to induce greater expression of CD69, two indicators of immune cell activation and regulation. The broad antiviral and adaptogenic properties of these herbs support their combined use to optimize immune function and support upper respiratory health.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152804151467,"sku":"80046957","price":27.99,"currency_code":"CAD","in_stock":true},{"title":"50 ml","offer_id":43152804184235,"sku":"80046955","price":17.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/utnz7wgl1xwjb1qy63pd.jpg?v=1749234688"},{"product_id":"urinary-pro","title":"Urinary-Pro","description":"Management of acute urinary tract infections\nContains a unique combination of four herbal extracts that promote healthy urinary function\nProvides 250 mg of bearberry (uva ursi) per tablet, standardized to 20% arbutin, with diuretic and antimicrobial properties\nBerberine hydrochloride enhances Nrf2 activity, promoting anti-inflammatory and antioxidant effects\nJuniper and berberine extracts both inhibit bacterial adhesion and biofilm formation\nEchinacea purpurea strengthens immune function and provides antiviral support\nSuitable for vegans\n\nUrinary-Pro provides clinical doses of four herbal extracts that support healthy urinary function. A unique combination of bearberry (uva-ursi), juniper, Echinacea purpurea, and berberine extracts promote antimicrobial and antioxidant activity along the urinary tract, inhibiting bacterial growth and adhesion while supporting immune function. Bearberry has the highest natural content of the phenol arbutin (hydroquinone beta-D-glucoside) and has a long history of use as a urinary antiseptic. The hydroquinone aglycone of arbutin, which is released in alkaline urine, is thought to provide its antimicrobial actions. In a clinical trial, women with recurrent cystitis were infection-free over a one-year period when consuming bearberry, compared to 23% of the placebo group. Berberine, well known for its antibacterial properties, has been shown to inhibit the adhesion of E. coli to human bladder cells, as well as bacterial biofilm formation by E. faecalis, in vitro. Berberine has also been shown to have anti-inflammatory effects and protect against oxidative damage, in part by enhancing the activity of nuclear factor erythroid-related factor 2 (Nrf2), a key signaling pathway for antioxidant defense.\u003cbr\u003e\u003cbr\u003eUrinary-Pro also provides a 4:1 extract of juniper, known for its antimicrobial, antioxidant, and diuretic properties, and has been shown to prevent the adhesion and growth of several bacterial species, including E. coli, in vitro. A 6:1 extract of Echinacea purpurea supports healthy urinary function by modulating innate and specific immune activity. In addition, it has been shown to have both antiviral and antibacterial properties.","brand":"Bioclinic Naturals","offers":[{"title":"60 Tablets","offer_id":43152804217003,"sku":"urinary-pro-bioclinic-naturals-60c","price":27.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/xrc8vsnstt5rpnocly5x.jpg?v=1749234687"},{"product_id":"berberine-hcl-500-mg","title":"Berberine (Berberine HCl) 500 mg","description":"Provides 500 mg of berberine hydrochloride per capsule, the dose used in clinical trials for glucose and lipid control.\nHypoglycemic effects through multiple mechanisms, including improved insulin sensitivity.\nFavorable effects on blood lipids, including a reduction in triglycerides and total and LDL cholesterol.\nActivation of Nrf-2, a key regulator of antioxidant gene transcription and prevention of glucose-induced neurotoxicity.\nBerberis vulgaris (European barberry) extract.\nSuitable for vegetarians\/vegans.\n\nTraditionally used for gastrointestinal symptoms, berberine has emerged as a potent cardiometabolic adjuvant with diverse benefits and mechanisms of action. It has hypoglycemic effects, via inhibition of alpha-glucosidase activity and an increase in insulin receptors in peripheral tissues, thus improving insulin sensitivity. In addition, it activates Nrf2, a key regulator of cellular antioxidant defense, and attenuates glucose-induced neurotoxicity, suggesting therapeutic potential for diabetic neuropathy.\u003cbr\u003e\u003cbr\u003eIn controlled trials, it reduced HbA1c levels in diabetic participants with comparable efficacy to metformin. In participants with metabolic syndrome, it was shown to reduce waist circumference and body weight, blood pressure, triglycerides, and improve insulin resistance compared to placebo, with similar benefits in women with PCOS. Berberine targets multiple cardiometabolic risk factors, as it has also been shown to reduce total cholesterol and LDL cholesterol in diabetic participants in several controlled trials. Additionally, a clinical trial comparing standard therapy with or without berberine in patients undergoing percutaneous coronary intervention showed improvements in several inflammatory markers, including C-reactive protein, IL-6, MMP-9, ICAM-1, and VCAM-1.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152804282539,"sku":"80051589","price":36.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/berberine-bioclinic-90c.png?v=1773254145"},{"product_id":"berberine-lipomicel-500-mg","title":"Berberine LipoMicel · 500 mg","description":"Provides 500 mg of berberine HCl per softgel, the dose used in clinical trials for glucose and lipid control.\nUses LipoMicel technology, which creates a matrix of liquid micelle dispersing berberine into tiny microdroplets, resulting in a highly stable delivery system for better absorption than standard forms.\nPromotes healthy glucose metabolism through multiple mechanisms, including improved insulin sensitivity. Has favorable effects on blood lipids, including a reduction in triglycerides and total and LDL cholesterol.\nActivates Nrf-2, a key regulator of antioxidant gene transcription and the prevention of glucose-induced neurotoxicity. Helps maintain cardiovascular health\nBerberis vulgaris (European barberry) extract\n\nAlthough berberine has traditionally been used to treat gastrointestinal symptoms, current research shows it is also beneficial for blood sugar regulation, cardiovascular health, and antioxidant activity. It helps lower blood sugar by slowing carbohydrate absorption and promoting insulin sensitivity, while lowering HbA1c levels. It contributes to reducing waist circumference and body weight, blood pressure, and triglycerides in metabolic syndrome. It also helps reduce blood pressure, total and LDL cholesterol, and triglyceride levels. \u003cbr\u003e\u003cbr\u003eBerberine improves insulin sensitivity by inhibiting alpha-glucosidase activity, increasing insulin receptors in peripheral tissues, activating AMPK, and inhibiting UHRF1. In controlled trials, it reduced HbA1c levels with comparable efficacy to standard treatment. Berberine also activates Nrf2, a key regulator of cellular antioxidant defense, and attenuates glucose-induced neurotoxicity.\u003cbr\u003e\u003cbr\u003eThe bioavailability of berberine supplements can vary considerably. Enhanced delivery forms, such as Berberine LipoMicel, enhance bioavailability, provide resistance to intestinal degradation, and may also improve intracellular delivery. A pilot crossover study showed that Berberine LipoMicel was effective in lowering blood glucose by 12% after two 500 mg doses.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152804315307,"sku":"80121912","price":44.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/dxjerswqr7cpjbe0fh5a.jpg?v=1749234684"},{"product_id":"pgx-r-weight-loss-meal-replacement-french-vanilla","title":"PGX® Weight Loss - Meal Replacement","description":"Low glycemic load and index; helps normalize postprandial blood sugar levels and improves insulin sensitivity to reduce fat storage. Suitable for low-carb diets. A delicious and satisfying meal replacement that suppresses appetite and prevents cravings. A convenient meal replacement for breakfast and\/or lunch. Contains 5g of PGX per serving. No artificial sweeteners or flavors. Also available in Double Chocolate or Vanilla.\n\nPGX Weight Loss Meal Replacement promotes healthy weight loss by reducing postprandial hyperglycemia, increasing satiety, and providing nutrients that support blood sugar metabolism. PGX (PolyGlycopleX) is a highly viscous combination of well-purified water-soluble polysaccharides derived from konjac root, sodium alginate, and xantham gum, which has been shown to reduce postprandial glucose concentrations and total and LDL cholesterol, primarily by forming a gel matrix that slows gastric emptying. Postprandial hyperglycemia is an important causative factor in endothelial dysfunction, several diabetic complications, and excess weight. By reducing the glycemic index of foods, viscous fiber prevents postprandial spikes in blood glucose concentration and insulin production. They have also been found to increase satiety and reduce appetite, promoting lower calorie intake, leading to weight loss.\u003cbr\u003e\u003cbr\u003ePGX is combined with whey protein and medium-chain triglycerides, which have been clinically shown to promote body fat loss while preserving lean muscle, and induce satiety and reduced calorie consumption, respectively. A comprehensive complement of vitamins and minerals ensures support for healthy macronutrient metabolism.","brand":"Bioclinic Naturals","offers":[{"title":"1 kg \/ Vanilla","offer_id":43152804610219,"sku":"pgx-meal-replacement-bioclinic-naturals-vanilla","price":59.99,"currency_code":"CAD","in_stock":true},{"title":"1 kg \/ Chocolate","offer_id":43183856255147,"sku":"pgx-meal-replacement-bioclinic-naturals-chocolat-1kg","price":59.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/wuutrmqcbf2gl1hpghwq.jpg?v=1749234683"},{"product_id":"mito-motile-male-wellness-kit","title":"Mito Motile Male Wellness Kit","description":"A comprehensive blend of antioxidants and nutrients to support sperm mitochondrial function, optimizing sperm maturation, count, and motility.\n\nProvides the most bioavailable forms of nutrients, including pyridoxal 5'-phosphate, vitamin D3, methylcobalamin, and L-5-methyltetrahydrofolate.\n\nProvides clinically relevant doses of nutrients for male fertility.\n\nPromotes glutathione production, essential for the detoxification of many toxins commonly associated with fertility disorders.\n\nReduces oxidative stress, which is closely linked to male infertility.\n\nMito Motile is a comprehensive male reproductive fertility support kit. This kit contains clinically relevant doses of vitamins and minerals, antioxidants and amino acids, essential fatty acids, and supporting nutrients essential for healthy male function. Mitochondrial dysfunction has been linked to increased oxidative damage, which is in turn closely linked to male infertility. Mito Motile contains several mitochondrial optimizers, including L-carnitine, PQQ-10®, and CoQ10, which have been shown to increase pregnancy rates and various parameters of sperm function. It provides powerful antioxidants, such as resveratrol, vitamin E, selenium, and N-acetylcysteine, nutrients that have been shown to protect against toxins that target spermatogenesis and improve sperm count, alone or in combination with clomiphene citrate. It also provides N-acetyl-L-cysteine ​​(a building block for the production of glutathione, a powerful antioxidant) to reduce oxidative stress and improve sperm quality. It contains zinc, an essential mineral for sperm count and motility, and to prevent oxidative stress and sperm DNA fragmentation. Its comprehensive nutritional support also includes clinically relevant doses of the omega-3 fatty acids DHA and EPA, which have been shown in human trials to improve total sperm count and concentration in men with idiopathic oligoasthenoteratospermia, as well as B vitamins to support energy production.","brand":"Bioclinic Naturals","offers":[{"title":"1 Kit","offer_id":43152804642987,"sku":"80093064","price":189.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/kgrxd7relw3xjr9dzcz8.jpg?v=1749234681"},{"product_id":"ultimate-prostate-support","title":"Ultimate Prostate Support","description":"Provides a combination of herbs and nutrients with broad support for prostate health.\nHerbs possess multiple mechanisms of action to limit inflammation and prostate enlargement.\nHelps relieve urologic symptoms associated with mild to moderate benign prostatic hyperplasia (BPH) (e.g., low urine flow, incomplete voiding, frequent urination during the day and night).\nStandardized ingredients to ensure potency.\nSoftgel allows for ease of use, with clinical doses.\n\nUltimate Prostate Support provides a unique and comprehensive blend of herbs and nutrients designed to support prostate health through complementary mechanisms. Saw palmetto, perhaps the most extensively studied herb, has been shown to bind to alpha-1 adrenergic receptors, inhibit 5α-reductase activity, and have an anti-inflammatory effect on the prostate. Several meta-analyses of randomized controlled trials support this. indicate that it provides symptom relief similar to standard therapies for benign prostatic hyperplasia (BPH) or chronic prostatitis, without the adverse effects on sexual function that can accompany standard treatment.\u003cbr\u003e\u003cbr\u003ePhytosterols also provide anti-inflammatory and antiproliferative effects. They have been shown to relieve symptoms of BPH when used alone and to enhance the effects of saw palmetto when used together. Nettle has anti-inflammatory and antioxidant properties, and also inhibits androgenic activity in the prostate, with several clinical trials supporting its use. Turmeric has potent anti-inflammatory activity and has been shown to improve prostate-related symptoms as part of combination therapies. Rye flower pollen extract and Pygeum africanum have anti-inflammatory and antiproliferative effects on the prostate, with clinical trial data indicating that they relieve prostate-related symptoms (often as part of combination therapies). Tomato extract provides numerous plant-derived antioxidants, including lycopene, which have been shown to have anti-inflammatory, antioxidant, and antiproliferative effects, as well as improve symptoms associated with prostatic hypertrophy.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152804675755,"sku":"ultimate-prostate-support-bioclinic-naturals-60c","price":45.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/c8dcvl8xgudmgryoiizo.jpg?v=1749234680"},{"product_id":"biofoundation-g-multiple-vitamin-mineral","title":"BioFoundation-G™ Multiple Vitamin \u0026 Mineral","description":"A Full Spectrum of Vitamins and Minerals\nProvides nutrients that limit the rate of glutathione production, necessary for the detoxification of xenobiotics.\nContains clinical doses of resveratrol, lipoic acid, CoQ10, milk thistle, and green tea extract.\nBroad-spectrum antioxidant support, including bilberry and citrus extracts, lipoic acid, lycopene, and lutein.\nHighly bioactive and bioavailable nutrients, such as pyridoxal-5-phosphate and vitamin K2 (menaquinone-7).\n\nBioFoundation-G is a comprehensive vitamin and mineral supplement designed to support a healthy lifestyle in the modern world. BioFoundation-G, a broad-spectrum, highly bioavailable multivitamin and mineral, is clinically researched to provide the nutritional foundation needed for the modern environment. This comprehensive multivitamin and mineral formula contains clinical doses of nutrients such as N-acetyl cysteine ​​and R-alpha lipoic acid, which have been shown to increase cellular levels of glutathione, the most prevalent intercellular antioxidant. Glutathione is one of the primary conjugates of many environmental and endogenous toxins and is known to be depleted not only by xenobiotics, but also by chronic diseases such as inflammatory and neurodegenerative diseases. \u003cbr\u003e\u003cbr\u003eGlutathione support is linked to lower rates of cell death and apoptosis. BioFoundation-G provides physiologically relevant doses of hepatoprotectors such as milk thistle, antioxidants, mitochondrial bioenergetic enhancers such as CoQ10, and cofactors for critical detoxification enzymes. It also provides the biological modifiers natural transresveratrol and green tea phytosome, two nutrients that have been shown to have anti-inflammatory, anti-aging, cardiovascular, and stress-related effects.","brand":"Bioclinic Naturals","offers":[{"title":"180 Tablets","offer_id":43152804839595,"sku":"80051438","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/lshx8ptnxibfre87jruy.jpg?v=1749234679"},{"product_id":"b12-methylcobalamin-1000-mcg","title":"B12 Methylcobalamin · 1000 mcg","description":"Methylcobalamin is the active form of vitamin B12 for maximum benefit.\nHigher bioavailability than the most common form, cyanocobalamin, which does not convert to sufficient methylcobalamin to correct certain forms of anemia, neurological defects, and aging.\n\nReduces homocysteine ​​levels for protective effects on the cardiovascular system.\n\nSublingual tablets provide rapid action directly into the bloodstream.\n\nVitamin B12 is a cofactor in enzymatic reactions with various physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as for the conversion of homocysteine ​​to methionine by methionine synthase, which is then converted to S-adenosylmethionine. B12 deficiency leads to deficiencies in both of these pathways, disrupting neurological function, including poor myelin sheath formation, the production of toxic levels of homocysteine, and inefficient energy production in all cells.\u003cbr\u003e\u003cbr\u003eMethylcobalamin, the major circulating form of B12 and the one transported to peripheral tissues, has been shown to reduce not only homocysteine ​​but also inflammatory factors and carotid artery plaque volume in stroke patients, as well as pain and neuropathy in diabetics. Because of its relationship to myelin production and neurological function, high-dose B12 has been used in a variety of neurodegenerative diseases, including Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. Some people, particularly those with malabsorption or low dietary intake, are at higher risk of B12 deficiency. People with poor B12 absorption rely on passive absorption, which typically accounts for 1% of the amount ingested. Therefore, higher doses may be necessary for those with higher B12 needs, such as the elderly and those with neurodegenerative disorders.","brand":"Bioclinic Naturals","offers":[{"title":"60 Sublingual Tablets","offer_id":43152804872363,"sku":"80026765","price":12.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/az9rmq6iocft3ljd6y7m.jpg?v=1749234677"},{"product_id":"b12-methylcobalamin-5000-mcg","title":"B12 Methylcobalamin · 5000 mcg","description":"Methylcobalamin is the active form of vitamin B12 for maximum benefit.\nHigher bioavailability than the most common form, cyanocobalamin, which does not convert to sufficient methylcobalamin to correct certain forms of anemia, neurological defects, and aging.\n\nReduces homocysteine ​​levels for protective effects on the cardiovascular system.\n\nSublingual tablets provide rapid action directly into the bloodstream.\n\nVitamin B12 is a cofactor in enzymatic reactions with various physiological functions. It is required for the conversion of methylmalonyl CoA to succinyl CoA, as well as for the conversion of homocysteine ​​to methionine by methionine synthase, which is then converted to S-adenosylmethionine. B12 deficiency leads to deficiencies in both of these pathways, disrupting neurological function, including poor formation of myelin sheaths, production of toxic levels of homocysteine, and inefficient energy production in all cells.\u003cbr\u003e\u003cbr\u003eMethylcobalamin, the major circulating form of B12 and the one transported to peripheral tissues, has been shown to reduce not only homocysteine, but also inflammatory factors and carotid artery plaque volume in stroke patients, as well as pain and neuropathy in diabetics. Due to its relationship with myelin production and neurological function, high-dose B12 has been used in various neurodegenerative diseases, including Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.\u003cbr\u003e\u003cbr\u003eSome people, particularly those with malabsorption or low dietary intake, are at greater risk of B12 deficiency. People with poor B12 absorption rely on passive absorption, which is typically 1% of the amount ingested. Therefore, higher doses may be necessary for people with higher B12 needs, such as the elderly and those with neurodegenerative disorders.","brand":"Bioclinic Naturals","offers":[{"title":"60 Sublingual Tablets","offer_id":43152804905131,"sku":"80041191","price":20.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/rnirujrmh5maucpiqfft.jpg?v=1749234677"},{"product_id":"enhanced-b-complex","title":"Enhanced B Complex","description":"Supports energy production, nutrient metabolism, liver function, immune function, and red blood cell production.\nSupports healthy hair, skin, and nails.\nContains a full spectrum of B vitamins in the most metabolically active forms, which do not require conversion by the liver for utilization.\nProvides a clinically effective dose of the most active and bioavailable form of folate, Quatrefolic.\nEach softgel also provides the most bioactive and bioavailable forms of each B vitamin, including methylcobalamin (B12), riboflavin 5'-phosphate (B2), and pyridoxal 5'-phosphate (B6).\nSuitable for vegetarians and vegans.\n\nEnhanced B Complex from Bioclinic Naturals is a once-daily formula that provides full-spectrum B vitamins in their most metabolically active forms. B vitamins are cofactors for many important body processes, including nutrient metabolism, energy production, growth and development, and liver function. B vitamins also contribute to immunity, red blood cell production, and iron metabolism, as well as healthy skin, hair, and nails. This formula contains active B vitamins, such as vitamins B12 (methylcobalamin) and B6 (pyridoxal 5'-phosphate), to support nervous system function. It also contains 50 mg of choline and 400 mcg of folate (Quatrefolic). In addition, this formula contains vitamins B1, B2, B5, and B6, plus niacin, with the added support of biotin and inositol. This convenient all-in-one B complex is an ideal supplement to help support metabolism, energy, and overall health. Quatrefolic acid is a cellularly active form of folate, the form found in the circulation and the only one to cross the blood-brain barrier. It may also be the optimal form for preventing neural tube defects. It does not need to be converted to the active form by the enzyme methylenetetrahydrofolate reductase (MTHFR), which is known to have common single-nucleotide polymorphisms. Administration of quatrefolic acid has been associated with higher peak levels of (6S)-5-MTHF than folic acid and calcium 5-MTHF, even in individuals with high-functioning MTHFR polymorphisms.\u003cbr\u003e\u003cbr\u003eMethylcobalamin is a cofactor for B12-dependent enzymes and has direct biological activity. When combined with other B vitamins, it reduces the risk of macular degeneration and migraines, with efficacy sometimes modulated by MTHFR status.\n","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152804937899,"sku":"80120273","price":22.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/g5o0kxc8zpmuqf1mr5em.jpg?v=1749234676"},{"product_id":"iron-bisglycinate","title":"Iron Bisglycinate","description":"Provides a clinical dose of 45 mg of elemental iron per capsule.\n\nThe highly absorbable form, iron bisglycinate chelate, has superior bioavailability compared to standard forms.\n\nComparable to ferrous sulfate at 1\/4 to 1\/2 the same dose of elemental iron.\n\nIron bisglycinate chelate is significantly better tolerated than commonly used forms, allowing for continued use and improving its effectiveness in replenishing iron stores.\n\nSuitable for vegetarians and vegans.\n\nIron deficiency remains the most common nutrient deficiency and the most common cause of anemia worldwide. Depleted iron stores impair mitochondrial function and cellular respiration even in the absence of anemia, particularly in metabolically active cells, contributing to symptoms ranging from fatigue and exercise intolerance to cognitive and cardiac impairment. In most cases, the primary means of replenishing iron levels is oral iron supplementation, which is preferable to parenteral administration (injections) in the absence of severe symptoms or contraindications.\nIn contrast, iron bisglycinate chelate, composed of two glycine molecules chelated to ferrous iron (Fe2+), has demonstrated significantly higher bioavailability than standard forms of iron such as ferrous sulfate, ferrous fumarate, and polymaltosed iron. This form is much better tolerated, allowing iron levels to be effectively restored using lower doses. For example, at ¼ to ½ the dose of ferrous sulfate, iron bisglycinate chelate has shown similar effects on hemoglobin, ferritin, and other markers of hematologic status in controlled trials, with improved tolerability. It has also been shown to be effective and well-tolerated in various patient populations, including pregnant women and children with celiac disease. 45 mg of elemental iron per capsule, higher than most formulations, is consistent with current recommendations for restoring depleted iron levels in pregnant women, although below the threshold generally associated with adverse effects.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152804970667,"sku":"80107078","price":18.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/whhqf6usgwal03roil3t.jpg?v=1749234675"},{"product_id":"liposomal-vitamic-c","title":"Liposomal Vitamin C","description":"1000 mg of vitamin C per two softgels\u003cbr\u003e\n\nLiposomes encapsulate vitamin C in a highly bioavailable lipid bilayer, exceeding plasma levels of standard supplements.\u003cbr\u003e\n\nLiposomes increase both peak plasma concentrations and total absorption of vitamin C.\u003cbr\u003e\n\nGentle form of vitamin C\u003cbr\u003e\n\nPowerful antioxidant, also supporting the immune system, collagen, and bones\u003cbr\u003e\n\nGMO and gluten-free\u003cbr\u003e\n\nLiposomal vitamin C is a highly bioavailable form of this essential antioxidant known to protect against oxidative damage, support healthy immune function, and play a critical role in collagen synthesis. Vitamin C is a cofactor for prolyl and lysyl hydroxylases, enzymes necessary for the development of collagen in joints and bones. High vitamin C intake has been linked to a reduced risk of osteoporotic fractures and increased bone mineral density. Vitamin C increases iron absorption, stabilizes vitamin E and folic acid, and reduces inflammation. An increased risk of deficiency has been identified in several populations, including the elderly, those with inflammatory bowel disease, cancer, or food allergies, and tobacco smokers. Vitamin C supplementation enhances immune function and is associated with a shorter duration of respiratory tract infections, such as the common cold. Supplementation has also been linked to improved liver function and blood sugar control in non-alcoholic fatty liver disease (NAFLD). Liposomes encapsulate vitamin C in a phospholipid bilayer, thereby circumventing the usual limitations of absorption and increasing plasma ascorbic acid levels to a greater extent than conventional supplementation. 8,9 Liposomal forms of vitamin C have been shown to nearly double the bioavailability while maintaining the safety of standard ascorbic acid supplementation.\u003cbr\u003e\n","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152805003435,"sku":"80121161","price":22.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/ykcn6mrgpr2xoyspntcd.jpg?v=1749234674"},{"product_id":"magnesium-bisglycinate-200-mg","title":"Magnesium Bisglycinate 200 mg","description":"The bisglycinate form of magnesium is more easily absorbed than salt forms such as magnesium oxide.1\n\nThe chelated form of bisglycinate is less likely to cause laxative effects than salt forms.1,2\n\nThe powder form allows for easy and convenient dosing away from food.\n\nThe vegetarian capsules provide 200 mg of elemental magnesium per capsule.\nNon-GMO and suitable for vegetarians\/vegans.\n\nSugar-free, with a pleasant taste due to citric acid in the powder form.\n\nMagnesium contributes to normal muscle function. It also supports metabolism, i.e., the ability to obtain energy from proteins, carbohydrates, and fats. Magnesium helps normalize blood pressure and fasting blood glucose, improve insulin sensitivity, and reduce the risk of developing type 2 diabetes mellitus, while also reducing blood pressure, hyperglycemia, and triglycerides in metabolic syndrome. Magnesium needs can be increased by stress, an unbalanced diet, coffee and alcohol consumption, and certain medications such as proton pump inhibitors. Therefore, it can be difficult to meet the body's daily magnesium needs through diet alone.\u003cbr\u003e\u003cbr\u003eIn a randomized, controlled trial, healthy older women were assigned to a treatment group receiving 300 mg of magnesium per day or a control group. After 12 weeks, the treatment group showed significant improvements in physical performance compared to the control group. The authors concluded that supplementation may play a role in preventing age-related physical decline. A double-blind, placebo-controlled trial showed that supplementing with 300 mg of magnesium bisglycinate daily for four weeks reduced the frequency and intensity of pregnancy-induced leg cramps. Magnesium is an important factor in muscle mass and repair and has been shown to relieve muscle cramps from a variety of causes.","brand":"Bioclinic Naturals","offers":[{"title":"145 g","offer_id":43152805036203,"sku":"80090179","price":21.99,"currency_code":"CAD","in_stock":true},{"title":"120 Capsules","offer_id":43152805068971,"sku":"80075249","price":27.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/uf7hfl36yxmoxf3bvh9p.jpg?v=1749234674"},{"product_id":"magnesium-citramal-150-mg","title":"Magnesium CitraMal™ · 150 mg","description":"Magnesium citrate has been shown to have superior bioavailability compared to other forms of magnesium, increasing its clinical efficacy.\n\nCitrate-malate complexes increase mineral absorption, particularly in individuals with reduced gastric acid secretion.\n\nMalic acid provides an important substrate in the citric acid cycle, helping to improve energy metabolism.\n\nConvenient dosage of 150 mg per capsule, allowing for easy therapeutic dosing.\n\nThe second most abundant intracellular cation and a cofactor for at least 600 enzymes, magnesium is a key regulator of numerous cellular functions, ion channels, signaling pathways, enzymes, and metabolic pathways, including glycolysis, fatty acid oxidation, and DNA synthesis. Extensive epidemiological data indicate that low magnesium intake is quite common and associated with various pathologies, particularly metabolic and inflammatory disorders and markers of inflammation, such as C-reactive protein and uric acid. Low magnesium intake has also been associated with an increased risk of hypertension, osteoporosis, stroke, cognitive impairment, and cardiovascular disease. Magnesium is particularly important for cardiovascular function, as it influences myocardial metabolism, calcium homeostasis, vascular tone, peripheral vascular resistance, and cardiac output. Magnesium supplementation has also been shown to promote cardiovascular health.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152805101739,"sku":"80026324","price":20.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/hh5kqesvyj12wzo4oshz.jpg?v=1749234673"},{"product_id":"prefoundation-prenatal-multiple-vitamin-mineral-formula","title":"PreFoundation™ Prenatal Multiple Vitamin \u0026 Mineral Formula","description":"Provides highly bioavailable forms and clinical doses of essential vitamins and minerals for optimal prenatal health.\nContains vitamins D3, K2 (menaquinone-7), and folate in the form of L-5-MTHF—key prenatal vitamins whose forms have been shown to be superior to those typically used in prenatal formulas.\nProvides citrate forms of key minerals, including magnesium, calcium, zinc, and copper, as well as 5'-phosphate forms of riboflavin and vitamin B6, and iron bisglycinate.\n\nPreFoundation provides a complete prenatal multivitamin\/mineral, with optimal dosages and bioavailable forms of each nutrient. Vitamin D3 has been shown to restore vitamin D levels more effectively than vitamin D2, with higher maternal vitamin D levels linked to a lower risk of ADHD, and supplementation linked to a lower risk of childhood wheezing and higher birth weight\/length. PreFoundation also provides L-5-MTHF, the bioactive form of folate, which bypasses the often-impaired enzymatic step required to activate folic acid. Consequently, pregnant women supplementing with L-5-MTHF have been shown to have higher red blood cell folate levels than those supplementing with folic acid. Better executive function has also been observed in children whose mothers supplemented with 5-MTHF during pregnancy.\nPotassium iodide is an essential source of iodine, which is often deficient in women but linked to children's cognitive development. Vitamin K2, in the form of menaquinone-7, is known to have a longer half-life than other forms of vitamin K and has been linked to greater osteocalcin carboxylation in children, which is essential for optimal bone health. PreFoundation also provides highly bioavailable forms of other vitamins and minerals essential for prenatal health, including the bioavailable citrate forms of calcium, magnesium, zinc, and copper, as well as the bisglycinate form of iron, which has been shown to be as effective during pregnancy as double the typically used iron dose. PreFoundation also provides superior forms of B vitamins, including vitamin B12 in the form of methylcobalamin, and the 5'-phosphate forms of riboflavin and vitamin B6.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152805134507,"sku":"prefoundation-bioclinic-naturals-90c","price":35.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/drum6wdghtsjwd646j76.jpg?v=1749234672"},{"product_id":"vitamin-d3-2500-iu","title":"Vitamin D3 · 2500 IU","description":"Vitamin D3 (cholecalciferol) is likely more effective at restoring blood levels than the D2 form (ergocalciferol).\nCholecalciferol has also been shown to increase the proportion of the active form of vitamin D compared to ergocalciferol.\n2,500 IU of vitamin D per softgel allows for easy daily dosing.\nEasy-to-swallow, highly bioavailable softgel.\nIn an organic flaxseed oil base for improved intestinal absorption.\n\nVitamin D is a hormone widely recognized as essential for many body systems and physiological processes. It may also be one of the most common nutritional deficiencies worldwide, with insufficient or deficient levels found in nearly 40% of Canadians. Vitamin D is essential for the proper functioning of the immune system and can reduce the risk and\/or severity of infections, particularly those of the respiratory tract, and particularly in individuals prone to infections. Many recent studies have linked lower levels of this vitamin to an increased risk of cardiovascular disease, including hypertension, peripheral vascular disease, and coronary heart disease. Vitamin D is needed to help absorb dietary calcium and is also important for bone health and muscle strength. Vitamin D has been linked to overall fitness and performance, with lower levels linked to frailty, particularly in older adults. Supplementation at clinically relevant doses has been associated with a well-established reduction in osteoporotic fractures. Given that virtually every tissue in the body possesses a vitamin D receptor, its importance is difficult to overestimate. Many practitioners recommend supplementation to achieve blood levels of 50 to 80 nmol\/L of 25-OH-vitamin D. This level often requires doses of 1,000 to 2,000 IU per day, and higher for people with common genetic variants affecting vitamin D metabolism.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152805167275,"sku":"80110516-90caps","price":10.99,"currency_code":"CAD","in_stock":true},{"title":"180 Capsules","offer_id":43152805200043,"sku":"80110516-180caps","price":18.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/jyhc4tz4eb3n9hfoy6yn.jpg?v=1749234671"},{"product_id":"vitamin-d3-1000-iu","title":"Vitamin D3 · 1000 IU","description":"Vitamin D3 (cholecalciferol) is likely more effective at restoring blood levels than the D2 form (ergocalciferol).\n1,000 IU of vitamin D per capsule allows for easy daily dosing.\nEasy-to-swallow, highly bioavailable capsule.\nIn an organic flaxseed oil base for improved intestinal absorption.\n\nVitamin D is a hormone now widely recognized as important for many body systems and a wide range of physiological processes. It may also be one of the most common nutritional deficiencies worldwide. Many recent studies have linked lower levels to an increased risk of cardiovascular disease, including hypertension, peripheral vascular disease, coronary artery disease, and heart failure, as well as several types of cancer, autoimmune diseases, and type 2 diabetes. Vitamin D is necessary for intestinal calcium absorption, skeletal bone integrity, and skeletal muscle strength and function, and has been linked to overall fitness. Vitamin D is essential for the proper function of the immune system and may reduce the risk of infection, particularly respiratory tract infections. Since virtually every tissue in the body has a receptor for vitamin D, its importance is difficult to overstate. Many practitioners recommend supplementation to achieve blood 25-OH-vitamin D levels between 50 and 80 nmol\/L, often requiring doses of 1,000 to 2,000 IU per day, and higher for people with common genetic variants affecting vitamin D metabolism.","brand":"Bioclinic Naturals","offers":[{"title":"180 Capsules","offer_id":43152805265579,"sku":"vitamine-d3-1000ui-bioclinic-naturals-180c","price":9.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/nayehak3ygb6lejmi2tv.jpg?v=1749234670"},{"product_id":"vitamin-d3-drops-1000-iu","title":"Vitamin D3 Drops · 1000 IU","description":"Vitamin D3 (cholecalciferol) is more effective at restoring blood levels than the D2 form (ergocalciferol).\nCholecalciferol has also been shown to increase the proportion of the active form of vitamin D compared to ergocalciferol.\n1000 IU of vitamin D per drop allows for easy daily dosing.\nIn a base of medium-chain triglycerides and organic flaxseed oil for better intestinal absorption.\n500 drops per bottle.\n\nVitamin D is a hormone now widely recognized as important for many body systems and a large number of physiological processes. It may also be one of the most common nutritional deficiencies worldwide. Many recent studies have linked lower levels to an increased risk of cardiovascular disease, including hypertension, peripheral vascular disease, coronary artery disease, and heart failure, as well as several types of cancer, autoimmune diseases, and type 2 diabetes. Vitamin D is necessary for intestinal calcium absorption, skeletal bone integrity, and skeletal muscle strength and function, and has been linked to overall fitness. Vitamin D is essential for the proper function of the immune system and may reduce the risk of infection, particularly respiratory tract infections. Since virtually every tissue in the body has a receptor for vitamin D, its importance is difficult to overstate. Many practitioners recommend supplementation to achieve blood 25-OH-vitamin D levels between 50 and 80 nmol\/L, often requiring doses of 1,000 to 2,000 IU per day, and higher for people with common genetic variants affecting vitamin D metabolism.","brand":"Bioclinic Naturals","offers":[{"title":"15 ml","offer_id":43152805298347,"sku":"vitamine-d3-1000ui-bioclinic-naturals-15ml","price":18.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/onadeyhca7njoddsceax.jpg?v=1749234670"},{"product_id":"vitamin-d3-drops-2500-iu","title":"Vitamin D3 Drops · 2500 IU","description":"Vitamin D3 (cholecalciferol) is more effective at restoring blood levels than the D2 form (ergocalciferol).\nCholecalciferol has also been shown to increase the proportion of the active form of vitamin D compared to ergocalciferol.\n2,500 IU of vitamin D per drop allows for easy daily dosing.\nIn a base of medium-chain triglycerides and organic flaxseed oil for improved intestinal absorption.\n\nVitamin D is a hormone now widely recognized as important for many body systems and a large number of physiological processes. It may also be one of the most common nutritional deficiencies worldwide. Many recent studies have linked lower levels to an increased risk of cardiovascular disease, including hypertension, peripheral vascular disease, coronary artery disease, and heart failure, as well as several types of cancer, autoimmune diseases, and type 2 diabetes. Vitamin D is necessary for intestinal calcium absorption, skeletal bone integrity, and skeletal muscle strength and function, and has been linked to overall fitness. Vitamin D is essential for the proper function of the immune system and may reduce the risk of infection, particularly respiratory tract infections. Since virtually every tissue in the body has a receptor for vitamin D, its importance is difficult to overstate. Many practitioners recommend supplementation to achieve blood 25-OH-vitamin D levels between 50 and 80 nmol\/L, often requiring doses of 1,000 to 2,000 IU per day, and higher for people with common genetic variants affecting vitamin D metabolism.","brand":"Bioclinic Naturals","offers":[{"title":"15 ml","offer_id":43152805331115,"sku":"vitamine-d3-2500ui-bioclinic-naturals-15ml","price":24.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/k3r1shbg7qt3gtvmgrjf.jpg?v=1749234666"},{"product_id":"vitamin-d3-k2-1000-iu-d3-120-mcg-k2","title":"Vitamin D3 \u0026 K2 · 1000 IU D3 · 120 mcg K2","description":"Provides clinically effective doses of vitamins D and K per capsule.\nVitamin D3 is the most potent form of vitamin D for increasing serum and storage levels.\nUses the optimal form of vitamin K, vitamin K2 menaquinone-7 (MK-7).\nMK-7 has the longest half-life and the best extrahepatic distribution of all forms.\nA combination of D3 and MK-7 offers a synergistic advantage over single-nutrient therapy.\n\nVitamin D and vitamin K have diverse and complementary physiological functions, close associations with chronic and age-related diseases, and a strong body of clinical evidence documenting widespread deficiency and therapeutic potential. Vitamin D has both hormonal and non-hormonal functions, with vitamin D receptors resulting in a myriad of physiological actions, ranging from bone metabolism to modulation of immune activity.\u003cbr\u003e\u003cbr\u003eVitamin D regulates the expression of hundreds of genes, influences cell proliferation and signaling, insulin production and sensitivity, and is a key inhibitor of several inflammatory pathways. Insufficiency has been linked to increased cardiovascular disease, cancer risk, diabetes, and metabolic syndrome, as well as overall mortality.\u003cbr\u003e\u003cbr\u003eVitamin K-dependent (VKD) proteins are also found almost ubiquitously and regulate diverse functions, including cell growth, arterial calcification, and bone metabolism.12 Clinically, low intakes are associated with an increased risk of cardiovascular disease, diabetes, cancer, fractures, and a variety of other diseases that cause mortality. Vitamins K and D have complementary physiological functions, and clinical trials have shown synergistic benefits for osteoporosis and cardiovascular disease when used together.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152805363883,"sku":"vitmaine-d3-k2-bioclinic-naturals-60c","price":21.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/o8jxqm1fnxjobqypstcg.jpg?v=1749234665"},{"product_id":"vitamin-k2-100-mcg","title":"Vitamin K2 · 100 mcg","description":"Provides 100 mcg per serving of vitamin K2 as menaquinone-7 (MK-7)\nMK-7 has the longest half-life of any vitamin K form, as well as the best extrahepatic distribution\nVitamin K2, particularly MK-7, allows for much lower dosing with significant clinical benefit\nNatto bean extract, the richest natural food-based MK-7\nSuitable for vegetarians\/vegans\n\nThe discovery of vitamin K-dependent (VKD) post-translational modifications of proteins involved not only in coagulation, but also in bone metabolism, vascular calcification, cell growth regulation, and even ATP production has radically changed the physiological and clinical importance of this enzyme cofactor. VKD cofactor proteins are present almost ubiquitously in various cell types, and modification by γ-carboxylation is required for biological activity. Dietary intake of vitamin K is often inadequate, and vitamin K is diverted to enzymes essential for short-term survival (e.g., coagulation), leading to suboptimal carboxylation of proteins associated with aging and chronic disease, such as matrix Gla protein, osteocalcin, and gas6. Clinically, lower vitamin K intake has been shown to be associated with a higher risk of myocardial infarction and stroke, plaque instability, and, more recently, diabetes. Higher vitamin K intake, particularly K2, has been associated with lower all-cause mortality, coronary heart disease, aortic calcification, and cancer incidence and mortality. Higher intake of MK-7, which has the longest half-life and the greatest extrahepatic distribution, was associated with a lower fracture risk and higher BMD.","brand":"Bioclinic Naturals","offers":[{"title":"90 Capsules","offer_id":43152805396651,"sku":"80040433","price":23.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/h6miufsjh67qimsod9ci.jpg?v=1749234663"},{"product_id":"l-glutamine-with-theracurmin","title":"L-Glutamine with Theracurmin™","description":"Provides 5g of L-glutamine and 30mg of Theracurmin per serving\u003cbr\u003e\n\nTargets multiple pathways of inflammation and protein synthesis to improve muscle repair and recovery after exercise.\u003cbr\u003e\n\nProvides immune and digestive system support\u003cbr\u003e\n\nTheracurmin has higher bioavailability and faster absorption in humans compared to standard curcumin1,2.\u003cbr\u003e\n\nThe powder formulation allows for flexible and convenient dosing.\u003cbr\u003e\n\nSuitable for vegetarians\/vegans\n\nL-glutamine combined with Theracurmin provides two complementary nutrients that target inflammation and support gut and musculoskeletal health, particularly in response to exercise. L-glutamine is the most abundant amino acid in the body, a Krebs cycle intermediate of particular importance to intestinal and immune cells, and is known to be depleted following intense physical activity. L-glutamine supplementation has been shown to prevent exercise-induced increases in intestinal permeability by promoting tight junction stability, increasing the production of anti-inflammatory cytokines, and suppressing inflammation, including NF-κB activation. L-glutamine also stimulates protein synthesis pathways while inhibiting protein breakdown, and has been shown to improve muscle recovery, reduce muscle soreness, and limit muscle damage after exercise. Curcumin has well-established anti-inflammatory effects on multiple molecular targets, including NF-κB, as well as cyclooxygenases and lipoxygenases, and it also promotes the restoration of intestinal integrity by enhancing tight junction protein expression. Curcumin supplementation has been shown to attenuate post-exercise muscle damage, reduce delayed-onset muscle soreness, and improve muscle performance recovery. Theracurmin, in particular, has been shown to prevent both increased creatine kinase and muscle breakdown after eccentric exercise. In a prospective clinical trial, theracurmin was effective in relieving symptoms and reducing the need for rescue medications in participants with knee osteoarthritis. Both L-glutamine and theracurmin target multiple mechanisms associated with inflammation, muscle repair, and muscle function.","brand":"Bioclinic Naturals","offers":[{"title":"306 g","offer_id":43152805593259,"sku":"80065236","price":43.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/phlns3nc0lsqyomvuxi7.jpg?v=1749234662"},{"product_id":"vitamin-d3-k2-and-a","title":"Vitamin D3, K2 and A","description":"Provides a balance of key fat-soluble vitamins, A, D, and K, essential for bone health.\nContains vitamin K2 (MK-7), the most bioactive and long-lasting form.\nK2 (MK-7) helps increase vertebral bone mineral density in postmenopausal women.\nProvides effective vitamin D3 to maintain blood levels of 25-OH vitamin D23.\nOptimal form of vitamin A, palmitate.\nSuitable for vegetarians.\n\nVitamins K2, D3, and A provide clinically relevant doses of the three fat-soluble vitamins essential for optimal bone health. While necessary for cardiovascular health, blood sugar regulation, immune function, and inflammation control, vitamins A, D3, and K2 have complementary physiological functions related to bone, such as modulating gene expression in osteoblasts and the carboxylation of osteocalcin, an enzyme required for bone formation. This is illustrated by a reduction in undercarboxylated osteocalcin and an increase in bone mineral density (BMD) in postmenopausal women when vitamin K2 is added to vitamin D3 supplementation. Vitamin D3 has diverse and important functions in multiple body systems, and widespread deficiency amplifies these crucial roles. Supplementation is associated with a well-established reduction in osteoporotic fractures. Correction of vitamin D3 deficiency is essential when supplementing with vitamin A, as vitamin A appears to promote bone health if vitamin D3 levels are adequate. Vitamin K2 is now recognized as being necessary not only for clotting, but also for the carboxylation of enzymes essential for bone and blood vessel health. Indeed, a meta-analysis showed an improvement in spinal BMD and a reduction in fractures in postmenopausal women with osteoporosis, while data from controlled trials show a reduction in age-related BMD decline in healthy postmenopausal women. The MK-7 form of vitamins K2, D3, and A has a longer half-life than any other form.","brand":"Bioclinic Naturals","offers":[{"title":"30 ml","offer_id":43152805822635,"sku":"80047935","price":23.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/f5pkhpwjpi2tablr7xyh.jpg?v=1749234662"},{"product_id":"dolor-ease","title":"Dolor Ease","description":"Comprehensive formula including white willow (Salix alba) bark extract, devil's claw, Theracurmin curcumin extract, and Boswellia (Boswellia serrata) extract.\nUsed in Herbal Medicine for the short-term relief of lower back pain.\nTraditionally used to relieve minor joint pain caused by osteoarthritis.\nContains 30 mg of Theracurmin, the most bioavailable form of curcumin, which provides natural antioxidant and anti-inflammatory support.\nIncludes InflamRelief, a natural source of antioxidants to protect joint tissue. Promotes Joint Health and Comfort\n\nDolor Ease is a comprehensive formula containing some of the best-known natural extracts used in herbal medicine to support joint health and temporarily relieve joint pain associated with osteoarthritis.\u003cbr\u003e\u003cbr\u003eWhite willow bark contains compounds such as salicin (chemically similar to aspirin) that have anti-inflammatory and analgesic effects. Research shows that white willow bark may be effective in providing short-term relief of lower back and joint pain associated with osteoarthritis.\u003cbr\u003e\u003cbr\u003eDevil's claw also contains compounds that, according to preliminary research, inhibit the inflammatory cascade. This extract has a long history of use in herbal medicine to help relieve joint pain associated with osteoarthritis.\u003cbr\u003e\u003cbr\u003eTheracurmin is a highly bioavailable form of curcumin‡, a natural compound with anti-inflammatory and antioxidant properties. Standard curcumin is poorly absorbed, but Theracurmin is produced using innovative proprietary technology to create small curcumin particles that significantly increase bioavailability.\nDolor Ease also contains InflamRelief, a source of antioxidants that helps protect joint cells and tissues from oxidative damage, as well as boswellia, a plant extract used in herbal medicine to support joint health.\u003cbr\u003e\u003cbr\u003eThe scientific review found Theracurmin to be more bioavailable, milligram for milligram, than other enhanced or regular forms of curcumin.","brand":"Bioclinic Naturals","offers":[{"title":"120 Capsules","offer_id":43152805986475,"sku":"80054434","price":43.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/ozma2l90qlukaei7wlll.jpg?v=1749234661"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/collections\/Unytii_Banniere_Collection_BioClinic_Naturals.jpg?v=1747856694","url":"https:\/\/www.unytii.com\/en\/collections\/collection-bioclinic-naturals-1.oembed?page=5","provider":"Unytii - Suppléments et Produits Naturels","version":"1.0","type":"link"}