{"title":"Alpha lipoic acid (ALA)","description":"","products":[{"product_id":"lipoic-acid-supreme-designs-for-health","title":"Lipoic Acid Supreme","description":"\nSupports carbohydrate, lipid, and protein metabolism\n\n\nLipoic Acid Supreme contains 300 mg of lipoic acid, along with 4 mg of pure biotin and 500 mg of taurine, and is designed to help maintain normal blood sugar and insulin balance. Lipoic acid is a sulfur-containing compound with amphiphilic antioxidant properties, making it effective in both water- and lipid-based environments. This unique property allows it to neutralize free radicals in both hydrophilic and lipophilic environments, such as the cytoplasm, plasma membranes, serum, and lipoproteins. Lipoic acid is best known for its antioxidant capacity, but this molecule has also been shown to have potent effects on blood sugar control via insulin secretion and sensitivity, while contributing to metal detoxification.\nMammals are capable of endogenous tissue synthesis of lipoic acid, but humans do so in very small amounts and are therefore better suited to absorbing it from exogenous sources. Furthermore, certain health conditions may benefit from higher amounts through supplementation, and lipoic acid has demonstrated safety at relatively high doses. The concentration of lipoic acid that generates pharmacological effects is higher than that generally bioavailable from food. The richest dietary sources of lipoic acid are metabolically active animal proteins, such as heart, liver, and kidney, all of which are limited in the modern Western diet.\n","brand":"Designs For Health","offers":[{"title":"60 Capsules","offer_id":41635713253547,"sku":"lipoic-acid-supreme-designs-for-health-60-capsules","price":64.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/Lipoic-Acid-Supreme-CN_60capsules-1.png?v=1749237122"},{"product_id":"meta-lipoate-300-metagenics","title":"Meta Lipoate-300","description":"\nHelps promote healthy glucose metabolism\n\n\n\nHelps promote healthy glucose metabolism.\nProvides antioxidants for the maintenance of good health.\n\n","brand":"Metagenics","offers":[{"title":"60 Tablets","offer_id":41636274503851,"sku":"meta-lipoate-300-metagenics-60-comprimés","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/metagenics_meta_lipoate_300_60t.jpg?v=1763569382"},{"product_id":"alpha-lipoic-acid-600-mg-pure-encapsulations","title":"Alpha Lipoic Acid 600 mg","description":"\nUnique fat- and water-soluble antioxidant\nSupports healthy glucose metabolism\nProvides 600 mg of alpha-lipoic acid per day\n\n\nAlpha-lipoic acid is an extremely versatile nutrient. Because it is both water- and fat-soluble, this multifunctional compound can be effective in virtually any part of the body. Alpha-lipoic acid supports healthy glucose metabolism by regulating enzymes involved in glucose oxidation. Maintaining healthy glucose metabolism is essential to prevent the formation of advanced glycation end products (AGEs), which reduce the efficiency of proteins, lipids, and nucleic acids. In addition to supporting healthy glucose metabolism, the antioxidant properties of alpha-lipoic acid also reduce oxidative stress, which is closely linked to AGE production and is a known contributor to many of the same health problems associated with AGEs. Alpha-lipoic acid scavenges free radicals and replenishes antioxidant vitamins C and E. This formula also includes vitamin C to further support and enhance the body's natural defense mechanisms against free radicals.\n","brand":"Pure Encapsulations","offers":[{"title":"60 Capsules","offer_id":41624504926379,"sku":"alpha-lipoic-acid-600-mg-pure-encapsulations-60-capsules","price":76.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/EnergiePLP-Produits_PureEncapsulations_0000s_0107_Alpha_Lipoic_Acid_600_mg.jpg?v=1749236739"},{"product_id":"alpha-lipoc-acid-acide-alpha-lipoique-400-mg-pure-encapsulations","title":"Alpha Lipoic Acid 400 mg","description":"\nUnique fat- and water-soluble antioxidant\nSupports healthy glucose metabolism\nProvides 400 mg of alpha-lipoic acid per day\n\n\nAlpha-lipoic acid is an extremely versatile nutrient. Because it is both water- and fat-soluble, this multifunctional compound can be effective in virtually any part of the body. Alpha-lipoic acid supports healthy glucose metabolism by regulating enzymes involved in glucose oxidation. Maintaining healthy glucose metabolism is essential to prevent the formation of advanced glycation end products (AGEs), which reduce the efficiency of proteins, lipids, and nucleic acids. In addition to supporting healthy glucose metabolism, the antioxidant properties of alpha-lipoic acid also reduce oxidative stress, which is closely linked to AGE production and is a known contributor to many of the same health problems associated with AGEs. Alpha-lipoic acid scavenges free radicals and replenishes antioxidant vitamins C and E. This formula also includes vitamin C to further support and enhance the body's natural defense mechanisms against free radicals.\n","brand":"Pure Encapsulations","offers":[{"title":"60 Capsules","offer_id":41624504664235,"sku":"alpha-lipoc-acid-acide-alpha-lipoique-400-mg-pure-encapsulations-60-capsules","price":68.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/EnergiePLP-Produits_PureEncapsulations_0000s_0108_Alpha_Lipoic_Acid_400_mg.jpg?v=1749236738"},{"product_id":"alamax-xymogen","title":"ALAmax","description":"\nProvides antioxidants for the maintenance of good health\nHelps promote healthy glucose metabolism\nHelps metabolize lipids, carbohydrates, and proteins\nHelps prevent biotin deficiency\n\n\nAlpha-lipoic acid (ALA) is a water- and fat-soluble eight-carbon disulfide compound that is synthesized in small amounts in the liver and other tissues. Oral supplementation readily crosses the blood-brain barrier after being absorbed in the small intestine, enters the portal vein, and is distributed via the systemic circulation. Once in tissues, ALA is found inside and outside cells, including within mitochondria where it naturally functions as a coenzyme for the oxidation of pyruvate, alpha-ketoglutarate, and branched-chain amino acids.\nResearchers have recently identified the mechanisms of action of lipoic acid related to the maintenance of metabolic health. It has a direct binding site at the tyrosine kinase domain of the insulin receptor. ALA appears to modulate 5'-AMP-activated protein kinase and PPAR-regulated genes, activate PPAR-alpha and PPAR-gamma, and support PPAR-gamma mRNA and protein expression in cardiac tissue and aortic smooth muscle.\nThe controlled-release technology supports the effectiveness of alpha-lipoic acid by helping to maintain blood glucose levels already within the normal range. Data from a 12-week clinical study indicate that supplementing with ALAmax CRTM (1200 mg daily, divided doses) can support healthy C-peptide levels. C-peptide is used as an indicator of insulin sensitivity.\nAlpha-lipoic acid effectively neutralizes a variety of free radicals, including oxygen radicals and ionized metals. This action is particularly beneficial for individuals with higher levels of oxidative stress. Alpha-lipoic acid replenishes vitamins C and E, increases glutathione levels in tissues, and helps maintain the proper ratio of reduced to oxidized coenzyme Q10 in mitochondria. Additionally, alpha-lipoic acid can help the body rid itself of heavy metals.\nHealthy endothelial-mediated vasodilation is accepted as a surrogate marker for cardiovascular health and may be affected by the synthesis, bioavailability, or action of nitric oxide (NO). Increased oxidative stress appears to play an important role in the neutralization or inactivation of NO. ALA's antioxidant properties, along with its demonstrated safety and potency, make it a prime candidate for evaluating its ability to support healthy endothelial function.\nAlpha-lipoic acid's ability to improve energy metabolism and reduce oxidative stress suggests its potential to support healthy mitochondrial function with aging.\nBiotin was added because chronic lipoic acid administration reduces the activities of pyruvate carboxylase and beta-methylcrotonyl-CoA carboxylase in vivo by competing with biotin.\n","brand":"Xymogen","offers":[{"title":"60 Tablets","offer_id":41624443551915,"sku":"alamax-xymogen-60-comprimés","price":104.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/ala-max-xymogen.png?v=1777899740"},{"product_id":"lipoic-acid-plus","title":"Lipoic Acid Plus","description":"Lipoic Acid Plus provides alpha-lipoic acid (ALA), a powerful antioxidant and a critical cofactor for many enzyme complexes, as well as vitamin C.\n\nLipoic Acid Plus provides alpha-lipoic acid (ALA), a powerful antioxidant and a critical cofactor for many enzyme complexes, as well as vitamin C. As a powerful biological antioxidant, lipoic acid has the ability to quench free radicals, equivalent to that of coenzyme Q10 (CoQ10) and vitamins C and E. In the body, it functions both as a coenzyme and as a necessary component for normal mitochondrial function. Unlike the actions of other antioxidants, including vitamins C and E, which are limited to aqueous and adipose tissues\/membranes, respectively, ALA has activity in both adipose and water-soluble tissues. When taken orally, lipoic acid is readily absorbed into both the cellular and tissue systems. ALA has also demonstrated beneficial effects in supporting both the cardiovascular system and glucose dysregulation. In terms of cardiovascular support, due to both its antioxidant function and its metal-chelating capacity, ALA's actions have been associated with the inhibition of endothelial activation, signifying its potential benefit in delaying both arterial plaque accumulation and adverse cardiovascular events. Its activity in supporting glucose dysregulation has been demonstrated in numerous studies. Lipoic acid is also involved in biological energy production and also possesses some heavy metal-chelating properties.","brand":"Biotics Research","offers":[{"title":"90 Capsules","offer_id":41902548713643,"sku":"lipoic-acid-plus-90-capsules","price":46.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/image_36638831-427f-4dcc-b265-73c9b028e97c.png?v=1749235423"},{"product_id":"cyto-ala","title":"Cyto ALA","description":"\n\n\u003cdiv class=\"e413-11 x-bar-content-area prod-excerpt\"\u003eNerve protection, blood sugar regulation, liver support, and detoxification benefits. All-in-one stable antioxidant compound for targeted support for your patients.\n\n\u003cdiv class=\"e413-11 x-bar-content-area prod-excerpt\"\u003eContains a pure and stable racemic mixture of alpha-lipoic acid (ALA), studied for its ability to regulate blood sugar, reduce symptoms of diabetic neuropathy, improve cognition, and aid detoxification through heavy metal binding and improved liver function.\n\n\u003cdiv class=\"e413-11 x-bar-content-area prod-excerpt\"\u003eProvides 600 mg of ALA per vegetarian capsule, allowing for simplified dosing and improved patient compliance.\n\n\u003cdiv class=\"e413-11 x-bar-content-area prod-excerpt\"\u003eThe addition of biotin and vitamin B1 prevents potential side effects or nutrient depletion that can occur with single-dose Long-term therapeutic ALA supplementation\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003e\n\u003c\/div\u003e\n\nFree radicals are omnipresent in our bodies thanks to the many environmental pollutants, toxins, processed foods, diseases, and daily stressors that surround us. Alpha-lipoic acid (ALA) is a powerful antioxidant capable of protecting us at the cellular level from these harmful free radicals.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eALA is a unique compound in that it is both fat-soluble and water-soluble, making its antioxidant activities functional both inside and outside the cell. This dual capacity makes ALA capable of regenerating a variety of other antioxidants in the body, such as vitamin E, vitamin C, coenzyme Q10, and glutathione. Regeneration is more important as we age because our bodies are less able to absorb and recycle these nutrients, as well as being more susceptible to the damaging effects of free radicals from the environment.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eClinical trials have shown ALA to be effective in a wide range of circumstances, including regulating blood sugar and reducing symptoms of peripheral neuropathy in people with diabetes. Research has also shown ALA to be useful in binding mercury, protecting the liver, reducing pain in peripheral artery disease, and improving cognitive function in people with Alzheimer's disease.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eThiamine, better known as vitamin B1, is also very supportive of the nervous system. In fact, it is well known that overt thiamine deficiencies can lead to peripheral neuropathy, and supplementing with various B1 forms is quite protective for the nerves, resulting in decreased pain, tingling, and numbness in people with diabetic neuropathy. Interestingly, research has shown that high doses of ALA can cause toxic side effects in people with thiamine deficiencies, making it necessary and wise to supplement the two nutrients together.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eFinally, biotin, a nutrient best known for supporting hair and skin tissue, should also be considered when discussing ALA supplementation. Research has shown that high supplemental doses of ALA alone can cause biotin deficiency, as each nutrient competes for absorption.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eCyto-Matrix's Cyto-ALA provides 600 mg of stable ALA per capsule. A low dose of thiamine and biotin is included to prevent deficiency and counteract potential side effects that can occur with therapeutic ALA dosing.","brand":"Cyto-Matrix","offers":[{"title":"60 Capsules","offer_id":42306929524907,"sku":"cyto-ala-60-capsules","price":39.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/image_864410b4-719d-45a4-ac0d-c625a81028ed.png?v=1749235258"},{"product_id":"alpha-lipoic-acid-vitazan-professional","title":"Alpha-Lipoic Acid","description":"\nProvides antioxidants for the maintenance of good health.","brand":"Vitazan Professional","offers":[{"title":"60 vegcaps","offer_id":45211645149355,"sku":"alpha-lipoic-acid-vitazan","price":20.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/0117-Alpha-Lipoic-Acid-250mg-60c.png?v=1749233656"},{"product_id":"r-alpha-lipoic-acid-vitazan-professional","title":"R+ Alpha-Lipoic Acid","description":"R-alpha-lipoic acid provides antioxidants for the maintenance of good health.","brand":"Vitazan Professional","offers":[{"title":"60 vegcaps","offer_id":45211645247659,"sku":"r+-alpha-lipoic-acid-vitazan","price":61.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/1376-R-Alpha-Lipoic-60-capsules-150-mg.png?v=1749233655"},{"product_id":"acide-r-lipoique-haute-dose","title":"High Dose R-Lipoic Acid","description":"\u003cul\u003e\n\n\u003cli\u003e\n\n\u003cp\u003eGlucose care and nerve health support\u003c\/p\u003e\n\n\n\u003c\/li\u003e\n\n\u003cli\u003e\n\n\u003cp\u003e R-lipoic acid is the naturally occurring and biologically active form of alpha-lipoic acid.\u003cbr\u003e\u003c\/p\u003e\n\n\n\u003c\/li\u003e\n\n\u003cli\u003e\n\n\u003cp\u003e Ideal for those looking to improve their glucose metabolism.\u003cbr\u003e\u003c\/p\u003e\n\n\n\u003c\/li\u003e\n\n\u003cli\u003e\n\n\u003cp\u003e Helps reduce\/relieve pain associated with diabetic neuropathy.\u003cbr\u003e\u003c\/p\u003e\n\n\n\u003c\/li\u003e\n\n\u003cli\u003e\n\n\u003cp\u003e 300 mg per delayed-release capsule.\u003c\/p\u003e\n\n\n\u003c\/li\u003e\n\n\n\u003c\/ul\u003e\n\u003cp\u003e Lipoic acid is a versatile antioxidant known for its ability to protect the brain and nerve cells from free radicals and heavy metals that contribute to cognitive and neurodegenerative diseases. Lipoic acid is known as the \"captain of antioxidants\" due to its ability to recycle and recharge other antioxidants such as vitamins C and E. Numerous studies have shown that lipoic acid can balance blood sugar and repair nerves damaged by diabetes.\u003c\/p\u003e\n\u003cp\u003e Additionally, this powerful anti-aging nutrient has been shown to mimic some of the effects of calorie restriction, the only proven method for extending lifespan and health. This product protects mitochondria from free radical damage and revitalizes damaged cells, especially those in the nerves and liver. It's an ideal partner for glutathione, the most powerful antioxidant produced by the body.\u003c\/p\u003e\n\u003cp\u003e In 1999, AOR was the first supplement manufacturer in the world to offer pure R-Lipoic Acid based on the most recent research.https:\/\/481954-1517251-raikfcquaxqncofqfm.stackpathdns.com\/wp-content\/uploads\/AOR-04005-R-Lipoic-Acid-150cc-Render-Side-1-NV01.00-1.png\u003c\/p\u003e\n\u003cp\u003e R-Lipoic acid is a powerful, natural, and multifaceted antioxidant – it repairs nerves, balances blood sugar, protects the brain, and increases energy production in mitochondria.\u003c\/p\u003e\n\u003cp\u003e AOR's pure R-lipoic acid provides the most effective form of this valuable antioxidant without the harmful effects of the S(–) form of lipoic acid. Regular doses of lipoic acid are recommended for the maintenance of general health, while high doses of R-lipoic acid are recommended for the treatment of problems related to hyperglycemia and diabetic neuropathy.\u003c\/p\u003e","brand":"AOR","offers":[{"title":"60 Capsules","offer_id":45513979068587,"sku":"r-lipoic-high-dose-aor-60c","price":62.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/AOR04289-High-Dose-R-Lipoic-Acid-60s-1.webp?v=1755026462"},{"product_id":"alpha-lipoic-acid-600mg-protocol-for-life","title":"Alpha Lipoic Acid 600mg","description":"\u003cp\u003eCette posologie de 600 mg est notre offre la plus puissante. Une glycémie élevée a été impliquée comme un indicateur avancé du syndrome métabolique, augmentant le risque d’un certain nombre de maladies dégénératives. Selon une enquête menée auprès de 685 herboristes, l’acide alpha-lipoïque était l’un des 10 compléments alimentaires les plus recommandés en raison de son efficacité à réduire les taux élevés de sucre dans le sang.\u003c\/p\u003e","brand":"Protocol For Life","offers":[{"title":"60vcaps","offer_id":45699897983147,"sku":"alpha-lipoic-acid-600mg-protocol-for-life-60vcaps","price":54.99,"currency_code":"CAD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/ce1ea335-e9b4-4561-a739-ef2e0d4eb172_443c74bf-6b10-4d02-8781-0386261817b7.png?v=1759846707"}],"url":"https:\/\/www.unytii.com\/en\/collections\/alpha-lipoic-acid-ala.oembed","provider":"Unytii - Suppléments et Produits Naturels","version":"1.0","type":"link"}