{"title":"5-HTP","description":"","products":[{"product_id":"cerenity-pm-ortho-molecular-products","title":"Cerenity PM","description":"\nCerenity PM is a comprehensive formulation created for patients suffering from occasional insomnia.\n\n\n\nUsed as a sleep aid.\nSpecifically formulated for patients suffering from occasional insomnia.\n\n","brand":"Ortho Molecular Products","offers":[{"title":"60 Capsules","offer_id":41632530759851,"sku":"cerenity-pm-ortho-molecular-products-60-capsules","price":80.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/EnergiePLP-Produits_Orthomolecular_0000s_0027_Cerenity_PM.jpg?v=1739819580"},{"product_id":"5-htp-supreme-designs-for-health","title":"5-HTP Supreme","description":"\nA combined formula of 5-hydroxytryptophan and vitamin B6\n\n\n5-hydroxytryptophan (5-HTP) is a precursor in the biosynthesis of serotonin. It is synthesized from L-tryptophan, an essential amino acid found naturally in dietary proteins such as turkey and milk, and requires vitamin B6 as a cofactor. 5-HTP is produced primarily by enterochromaffin cells in the gastrointestinal tract and by the raphe nuclei of the brainstem, where it is subsequently converted to serotonin. Serotonin produced in the gastrointestinal tract stimulates physiological functions including vasoconstriction, uterine contraction, bronchoconstriction, gastrointestinal motility, and platelet aggregation. At the brain level, serotonin inhibits excitatory neurotransmission and modulates wakefulness, attention, psychological attitude (anxiety and depression), sexual behavior, appetite, thermoregulation, motor skills, migraines, vomiting, nociception, and aggression.\n","brand":"Designs For Health","offers":[{"title":"60 Capsules","offer_id":41624403640491,"sku":"5-htp-supreme-designs-for-health-60-capsules","price":73.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/5HTP-Supreme-CN_60capsules-1.png?v=1749237166"},{"product_id":"5-htp-synergy-designs-for-health","title":"5-HTP Synergy","description":"\nA combined formula of 5-hydroxytryptophan and vitamin B6\n\n\n5-hydroxytryptophan (5-HTP) is a precursor in the biosynthesis of serotonin. It is synthesized from L-tryptophan, an essential amino acid found naturally in dietary proteins such as turkey and milk, and requires vitamin B6 as a cofactor. 5-HTP is produced primarily by enterochromaffin cells in the gastrointestinal tract and by the raphe nuclei of the brainstem, where it is subsequently converted to serotonin. Serotonin produced in the gastrointestinal tract stimulates physiological functions including vasoconstriction, uterine contraction, bronchoconstriction, gastrointestinal motility, and platelet aggregation. At the brain level, serotonin inhibits excitatory neurotransmission and modulates wakefulness, attention, psychological attitude (anxiety and depression), sexual behavior, appetite, thermoregulation, motor skills, migraines, vomiting, nociception, and aggression.\n","brand":"Designs For Health","offers":[{"title":"90 Capsules","offer_id":41624404525227,"sku":"5-htp-synergy-designs-for-health-90-capsules","price":55.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/5htp-synergy-design-for-health-90c.png?v=1782741899"},{"product_id":"serosyn-metagenics","title":"SeroSyn","description":"\nSupports a healthy, balanced mood\n\n\n\n5-HTP contributes to a balanced mood.\nTheanine helps temporarily promote relaxation.\nPanax Ginseng helps support cognitive function and reduce mental fatigue.\n\n","brand":"Metagenics","offers":[{"title":"90 Capsules","offer_id":11069517594667,"sku":"serosyn-metagenics-90-capsules","price":102.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/metagenics_serosyn_90c.jpg?v=1763570350"},{"product_id":"seroplus-pure-encapsulations","title":"SeroPlus","description":"\nComprehensive Support for Healthy Mood Balance\nContains 5-HTP, a precursor to serotonin\nContains the following cofactors: vitamin C, vitamin B6, zinc, and folate (Metafolin® L-5MTHF)\n\n\nSeroPlus was created by Pure Encapsulations in collaboration with Dr. James Greenblatt as part of the Integrative Mental Health Series, a line of products based on scientific discoveries and decades of clinical experience. SeroPlus contains 5-HTP to support healthy mood balance by providing essential building blocks for serotonin. By helping to form serotonin, 5-HTP balances serotonin activity in the brain, promoting emotional well-being. Another key element of each formulation in this series is the inclusion of cofactors such as vitamin B6, zinc, and Metafolin® L-5-MTHF. L-5-MTHF is a form of folate that easily crosses the blood-brain barrier. These nutrients are often deficient due to medications, poor diets, and exposure to toxic environments, compromising the ability to efficiently metabolize nutrients. Along with zinc, vitamin B6 is a cofactor in amino acid metabolism, including the metabolism of 5-HTP to serotonin.\n","brand":"Pure Encapsulations","offers":[{"title":"120 Capsules","offer_id":41636912169131,"sku":"seroplus-pure-encapsulations-120-capsules","price":59.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/EnergiePLP-Produits_PureEncapsulations_0000s_0018_SeroPlus.jpg?v=1749236797"},{"product_id":"ac-capsules-xymogen","title":"AC Capsules","description":"\nPromotes healthy glucose metabolism\nSource of amino acids involved in muscle protein synthesis\nHelps maintain healthy mood balance\n\n\n5-Hydroxytryptophan (\"5-HTP\") is a natural amino acid precursor of serotonin. Numerous studies during the 1990s, including randomized, double-blind, and placebo-controlled studies, confirmed the safety and efficacy of 5-HTP in reducing appetite and food intake in healthy, obese, diabetic individuals with non-insulin-dependent leptin secretion. Vitamins B6 and C are important cofactors in the 5-HTP serotonin pathway. Among the many serotonin receptors identified, 5HT2C receptors are suspected of controlling food intake. Mice lacking this receptor exhibit increased food consumption and become obese.\nDL-Phenylalanine (DLPA) is a combination of the d- and l-forms of this essential amino acid. Phenylalanine suppresses appetite by regulating the release of cholecystokinin, which in turn signals satiety in the brain. D-Phenylalanine increases endorphins, while L-Phenylalanine is an amphetamine-like stimulant compound. DLPA has been shown to improve mood, curb appetite, and reduce pain.\nL-Tyrosine, an essential amino acid, is required for conversion to the stress-relieving catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine. It is also a precursor to thyroxine. Doctors use tyrosine as a mood elevator, to increase alertness after sleep deprivation, and as an appetite suppressant; although support for the latter appears anecdotal.\nL-Glutamine, known for its gut and immune support, has also been adopted to reduce carbohydrate cravings and aid in alcohol withdrawal, although the mechanism of action for these benefits is unknown.\nChromium, as chromium picolinate, is widely used to optimize insulin function, thus preventing blood sugar fluctuations that can be responsible for carbohydrate cravings. In fact, the mineral in its present form has been shown to reduce carbohydrate cravings in a double-blind, placebo-controlled study.\n","brand":"Xymogen","offers":[{"title":"120 Capsules","offer_id":41624408359083,"sku":"ac-capsules-xymogen-120-capsules","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/ac-capsules-xymogen.png?v=1777898922"},{"product_id":"5-htp-sap-50mg-nfh","title":"5-HTP SAP 50mg","description":"\nScience-Based Serotonin Precursor\n\n\nSerotonin, or 5-hydroxytryptamine (5-HT), is a monoaminergic neurotransmitter involved in several crucial physiological processes, including the modulation of mood, cognition, sleep, appetite, learning, memory, and vasoconstriction.\n\u003cstrong\u003e5-HTP SAP\u003c\/strong\u003e may:\u003cbr\u003e\n\nPromote mood balance\nHelp relieve symptoms of fibromyalgia\nBe used as a sleep aid\nHelp reduce the severity and duration of migraines when taken prophylactically\n","brand":"NFH","offers":[{"title":"90 Capsules","offer_id":41624403083435,"sku":"5-htp-sap-50mg-nfh-90-capsules","price":24.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/1669-5-HTP-SAP-50mg-90-capsules.jpg?v=1749236511"},{"product_id":"5-htp-sap-100mg-nfh","title":"5-HTP SAP 100mg","description":"\nScience-Based Serotonin Precursor\n\n\nSerotonin, or 5-hydroxytryptamine (5-HT), is a monoaminergic neurotransmitter involved in several crucial physiological processes, including the modulation of mood, cognition, sleep, appetite, learning, memory, and vasoconstriction.\n5-HTP SAP can:\n\nPromote mood balance.\nHelp relieve symptoms of fibromyalgia.\nBe used as a sleep aid.\nHelp reduce the severity and duration of migraines when taken prophylactically.\n","brand":"NFH","offers":[{"title":"90 Capsules","offer_id":41624402624683,"sku":"5-htp-sap-100mg-nfh-90-capsules","price":36.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/5-HTP-SAP-100mg-90-capsules.jpg?v=1749236510"},{"product_id":"5-htp-aor","title":"5-HTP","description":"\nPromotes a positive mood\nA precursor to serotonin\nPromotes mood balance and healthy sleep patterns\nRelieves migraines and fibromyalgia symptoms\nFlexible dosage, adaptable to individual needs\n\n\n5-HTP is primarily used to support mood, as it is able to increase serotonin levels. Compared to various tricyclic antidepressants, this molecule has been shown to be as effective and faster-acting, with fewer side effects. Since serotonin and melatonin are involved in regulating the sleep-wake cycle, 5-HTP also improves sleep quality. Additionally, research has shown that 5-HTP plays a role in reducing fibromyalgia symptoms and migraine frequency. Studies conducted in Spain and Italy have shown that 5-HTP is comparable to methysergide, a medication that relieves migraine symptoms (over 70% in both groups) with fewer side effects. Fibromyalgia patients have been found to have low serotonin levels, and their symptoms improved with the use of tricyclic and SSRI antidepressants. Numerous clinical trials of 5-HTP have also confirmed significant improvements in symptoms, including pain, morning stiffness, nervousness, and fatigue.\nAOR's 5-HTP is a natural compound extracted from Griffonia simplicifolia seeds and is available in two dosage formats to cover a wide range of dosing options, adaptable to individual needs.\n","brand":"AOR","offers":[{"title":"90 Capsules","offer_id":41624395874475,"sku":"5-htp-aor-90-capsules","price":37.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/image_17979bd8-2e04-4549-ab03-48c20d0597c0.png?v=1749236395"},{"product_id":"pro-5-htp-100","title":"PRO 5-HTP 100","description":"Fatigue, nutritional deficiencies, mitochondrial dysfunction\n\nPRO B-Complex contains essential B vitamins that play important roles in the body, such as promoting metabolic and nerve health, providing stress support, and other essential functions.\u003cbr\u003e\u003cbr\u003eB-Complex supplementation is helpful in preventing deficiencies associated with type 2 diabetes, neurological disorders, anemia, depression, neuropathy, stress, and neural tube birth defects. B-Complex supplementation also strongly promotes metabolic support, diabetic support, and stress management, among other key functions.\u003cbr\u003e\u003cbr\u003ePRO B-Complex provides the most biologically active and effective forms of these vitamins at balanced doses, ensuring maximum benefits.","brand":"AOR PRO","offers":[{"title":"90 Capsules","offer_id":42543427059883,"sku":"pro-5-htp-100-aor-pro-90-capsules","price":46.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/AOR34029-Pro5-HTP10090s-150ccWraparound-Render-Front-CAN-NV01.20.png?v=1749235164"},{"product_id":"aor34186","title":"Pro Sleep","description":"Improves overall sleep.\n\nThe most comprehensive and natural sleep formula available\nHelps you fall asleep, stay asleep, and wake up refreshed\nSupports circadian rhythm regulation\nPromotes nervous system relaxation\n\nPro Sleep is a comprehensive sleep formula that addresses multiple mechanisms of circadian rhythm regulation and nervous system relaxation while supporting anti-anxiety pathways. The combination of key neurotransmitters and precursors such as GABA, 5-HTP, and L-theanine, in addition to melatonin and powerful relaxing botanicals such as valerian, passion flower, and lemon balm, synergistically helps reduce sleep latency and improve sleep quality. Pro Sleep is helpful for those who have difficulty falling asleep, staying asleep, or waking up refreshed, and can be particularly helpful for jet lag, shift work, and insomnia. AOR Advantage\nMany sleep formulas contain only melatonin, or can only address one aspect of sleep. If you've been using the individual ingredients in this formula without success, Pro Sleep may offer a more effective natural solution because it's been specifically formulated to be the most comprehensive natural sleep aid available. It effectively addresses short-term sleep disturbances due to anxiety, stress, or circadian rhythm disruption, as well as long-term factors such as shift work and jet lag. Due to its unprecedented potency, Pro Sleep should only be used as directed.","brand":"AOR PRO","offers":[{"title":"60 Capsules","offer_id":42906023919787,"sku":"pro-sleep-aor-60-capsules","price":45.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/AOR-34186-Pro-Sleep-150cc-2-Ply-Render-Front-CAN-NV01.00.png?v=1749234833"},{"product_id":"5-htp-100-mg","title":"5-HTP 100 mg","description":"Extra-strength 100 mg formula for ease of dosing\nNaturally sourced from the seed of the African plant Griffonia simplicifolia\n5-HTP easily crosses the blood-brain barrier to increase serotonin synthesis in the central nervous system.\nThe delayed-release formulation can minimize gastric discomfort and helps prevent the rapid spikes and drops associated with immediate-release 5-HTP.\n\n5-HTP (5-hydroxytryptophan) is an amino acid precursor to the brain chemical serotonin, a neurotransmitter essential for balancing mood and performing cognitive tasks such as learning and memory formation. Low mood and other conditions have long been associated with low serotonin levels, making 5-HTP an attractive natural option for elevating mood and improving emotional health. Extended-release tablets overcome the limitations of immediate-release formulations. This allows for a sustained increase in serotonin, avoiding the rapid spikes, fluctuations, and drops associated with missing or delayed dosing. Additionally, extended-release preparations may help minimize the gastric discomfort some people experience with 5-HTP.\nClinical research supports 5-HTP supplementation for mood. A randomized, double-blind clinical trial of 60 patients evaluated the effectiveness of 5-HTP supplementation compared to fluoxetine. Efficacy was determined by comparing HAM-D scores at baseline with those after 2 weeks, 4 weeks, and 8 weeks. After 5-HTP supplementation, 73% of patients taking 5-HTP and 80% of patients taking fluoxetine showed a significant reduction in HAM-D scores from the second week through the end of the study.\u003cbr\u003e\u003cbr\u003e5-HTP has also been used to treat serotonin imbalance implicated in chronic pain, including migraines, as well as fibromyalgia and insomnia. People with fibromyalgia who take 300 to 400 mg of 5-HTP daily in divided doses have reported improvements in symptoms, including pain intensity, morning stiffness, and insomnia. 5-HTP is known to improve sleep quality, which is essential for people with fibromyalgia. In fact, 5-HTP has been shown to promote REM sleep in healthy adults. Increasing the time spent in REM sleep is one of the reasons why 5-HTP is considered a sleep aid.","brand":"Bioclinic Naturals","offers":[{"title":"60 Capsules","offer_id":43152806936747,"sku":"80095817","price":30.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/products\/wcpzdg8nqivc0aegvwoe.jpg?v=1749234657"},{"product_id":"sleep-like-buddha","title":"Sleep like Buddha","description":"Natural sleep aid capsule made in Canada\u003cbr\u003e\n\nSpecifically formulated for stress-related sleep problems\u003cbr\u003e\n\nMelatonin-free - no groggy mornings or hangovers\u003cbr\u003e\n\nFights \"busy brain\" and sleep-related anxiety\u003cbr\u003e\n\nPromotes relaxation and mood balance\n\nUse Sleep Like Buddha without melatonin alone or pair it with Daytime Zen, a natural stress-relieving supplement made with adaptogens, for even better results.","brand":"Niyama","offers":[{"title":"60 capsules","offer_id":43526928138411,"sku":"sleep-like-buddha-niyama-60-capsules","price":42.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2993\/1664\/files\/sleep-like-buddha_Niyama_Energieplp_unytii_Supplements.webp?v=1749234550"}],"url":"https:\/\/www.unytii.com\/en\/collections\/5-htp.oembed","provider":"Unytii - Suppléments et Produits Naturels","version":"1.0","type":"link"}